Richard M Cripps
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Explore the profile of Richard M Cripps including associated specialties, affiliations and a list of published articles.
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53
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895
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Recent Articles
1.
Robinson E, Alonso E, A Waters J, Bileckyj C, House C, Johnston C, et al.
Biotechniques
. 2024 Aug;
76(7):299-309.
PMID: 39185782
Epitope tagging represents a powerful strategy for expedited identification, isolation, and characterization of proteins in molecular biological studies, including protein-protein interactions. We aimed to improve the reproducibility of epitope-tagged protein...
2.
Trujillo E, Lee S, Aguayo A, Torosian T, M Cripps R
Dev Biol
. 2024 Aug;
516():82-95.
PMID: 39111615
The Myocyte enhancer factor-2 (MEF2) transcription factor plays a vital role in orchestrating muscle differentiation. While MEF2 cannot effectively induce myogenesis in naïve cells, it can potently accelerate myogenesis in...
3.
Bileckyj C, Blotz B, M Cripps R
J Cardiovasc Dev Dis
. 2023 Dec;
10(12).
PMID: 38132661
The genetic model system Drosophila has contributed fundamentally to our understanding of mammalian heart specification, development, and congenital heart disease. The relatively simple Drosophila heart is a linear muscular tube...
4.
Lovato T, Blotz B, Bileckyj C, Johnston C, M Cripps R
Dis Model Mech
. 2023 Sep;
16(9).
PMID: 37691628
Sequencing of human genome samples has unearthed genetic variants for which functional testing is necessary to validate their clinical significance. We used the Drosophila system to analyze a variant of...
5.
Wong-Welch J, M Cripps R
Biochem Mol Biol Educ
. 2023 Aug;
51(6):635-643.
PMID: 37584429
Three dimensional (3D) design and printing are customizable and cost-effective approaches to developing small equipment and other items for use in various interdisciplinary applications. However, many pedagogical approaches to 3D...
6.
Lovato T, Blotz B, Bileckyj C, Johnston C, M Cripps R
bioRxiv
. 2023 Jul;
PMID: 37425758
Sequencing of human genome samples has unearthed genetic variants for which functional testing is necessary to validate their clinical significance. We used the Drosophila system to analyze a variant of...
7.
Vishal K, Alonso E, DeAguero A, A Waters J, Chechenova M, M Cripps R
Mol Cell Biol
. 2023 May;
43(6):241-253.
PMID: 37184381
Activity of the myogenic regulatory protein myocyte enhancer factor-2 (MEF2) is modulated by post-translational modification. We investigated the in vivo phosphorylation of MEF2, and identified serine 98 (S98) as a...
8.
Bu L, M Cripps R
PLoS One
. 2022 Jul;
17(7):e0271554.
PMID: 35862472
To gain understanding into the mechanisms of transcriptional activation of muscle genes, we sought to determine if genes targeted by the myogenic transcription factor Myocyte enhancer factor-2 (MEF2) were enriched...
9.
Czajkowski E, Cisneros M, Garcia B, Shen J, M Cripps R
Dev Dyn
. 2020 Sep;
250(1):99-110.
PMID: 32893414
Background: To identify novel myofibrillar components of the Drosophila flight muscles, we carried out a proteomic analysis of chemically demembranated flight muscle myofibrils, and characterized the knockdown phenotype of a...
10.
Vaziri P, Ryan D, Johnston C, M Cripps R
Genetics
. 2020 Aug;
216(1):177-190.
PMID: 32753389
Myosin is an essential motor protein, which in muscle is comprised of two molecules each of myosin heavy-chain (MHC), the essential or alkali myosin light-chain 1 (MLC1), and the regulatory...