Richard Laga
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Explore the profile of Richard Laga including associated specialties, affiliations and a list of published articles.
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30
Citations
741
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Recent Articles
1.
Pytlikova S, Konefal R, Pola R, Braunova A, Lobaz V, Slouf M, et al.
ACS Appl Bio Mater
. 2024 Dec;
8(1):271-284.
PMID: 39661715
The development of stimuli-responsive drug delivery systems enables targeted delivery and environment-controlled drug release, thereby minimizing off-target effects and systemic toxicity. We prepared and studied tailor-made dual-responsive systems (thermo- and...
2.
Sivkova R, Konefal R, Kostka L, Laga R, Garcia-Briones G, Kockova O, et al.
Macromol Rapid Commun
. 2024 Nov;
46(2):e2400640.
PMID: 39491052
Poly(2-(N,N-dimethylamino)ethyl acrylate) (PDMAEA) is a promising charge-shifting polycation with the capacity to form a range of morphologically distinct polyelectrolyte assemblies. Nevertheless, the basic character of the monomer and its hydrolytic...
3.
Mixova G, Tihlarikova E, Zhu Y, Schindler L, Androvic L, Kracikova L, et al.
Bioconjug Chem
. 2024 Jul;
35(8):1218-1232.
PMID: 39081220
Minimal immunogen vaccines are being developed to focus antibody responses against otherwise challenging targets, including human immunodeficiency virus (HIV), but multimerization of the minimal peptide immunogen on a carrier platform...
4.
Kracikova L, Androvic L, cerveny D, Jirat-Ziolkowska N, Babic M, Svabova M, et al.
Sci Rep
. 2024 Feb;
14(1):3847.
PMID: 38360883
In this work, we present the synthesis and evaluation of magnetic resonance (MR) properties of novel phosphorus/iron-containing probes for dual P and H MR imaging and spectroscopy (MRI and MRS)....
5.
Pechar M, Kral V, Kracikova L, Androvic L, Hrda E, Pola R, et al.
Int J Pharm
. 2023 Nov;
648:123619.
PMID: 37979631
Antibody-mediated targeting is an efficient strategy to enhance the specificity and selectivity of polymer nanomedicines towards the target site, typically a tumor. However, direct covalent coupling of an antibody with...
6.
Kracikova L, Androvic L, Potockova I, Ziolkowska N, Vit M, cerveny D, et al.
Molecules
. 2023 Mar;
28(5).
PMID: 36903579
The visualization of organs and tissues using P magnetic resonance (MR) imaging represents an immense challenge. This is largely due to the lack of sensitive biocompatible probes required to deliver...
7.
Kracikova L, Ziolkowska N, Androvic L, Klimankova I, cerveny D, Vit M, et al.
Macromol Biosci
. 2022 Mar;
22(5):e2100523.
PMID: 35246950
P-magnetic resonance (MR) is an important diagnostic technique currently used for tissue metabolites assessing, but it also has great potential for visualizing the internal body structures. However, due to the...
8.
Ziolkowska N, Vit M, Laga R, Jirak D
Sci Rep
. 2022 Feb;
12(1):2118.
PMID: 35136162
We present the MR properties of a novel bio-responsive phosphorus probe doped with iron for dual proton and phosphorus magnetic resonance imaging (H/P-MRI), which provide simultaneously complementary information. The probes...
9.
Sur V, Mazumdar A, Vimberg V, Stefani T, Androvic L, Kracikova L, et al.
Int J Mol Sci
. 2022 Jan;
23(1).
PMID: 35008521
Teicoplanin is a natural lipoglycopeptide antibiotic with a similar activity spectrum as vancomycin; however, it has with the added benefit to the patient of low cytotoxicity. Both teicoplanin and vancomycin...
10.
Williams W, Meyerhoff R, Edwards R, Li H, Manne K, Nicely N, et al.
Cell
. 2021 May;
184(11):2955-2972.e25.
PMID: 34019795
Natural antibodies (Abs) can target host glycans on the surface of pathogens. We studied the evolution of glycan-reactive B cells of rhesus macaques and humans using glycosylated HIV-1 envelope (Env)...