Richard L Klein
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Explore the profile of Richard L Klein including associated specialties, affiliations and a list of published articles.
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62
Citations
1839
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Recent Articles
1.
Lopes-Virella M, Hammad S, Baker N, Klein R, Hunt K
Biomedicines
. 2024 Jan;
12(1).
PMID: 38255295
Abnormalities of sphingolipid metabolism play an important role in diabetes. We compared sphingolipid levels in plasma and in isolated lipoproteins between healthy control subjects and two groups of patients, one...
2.
Baker N, Hammad S, Hunt K, Semler A, Klein R, Lopes-Virella M
Diabetes
. 2022 May;
71(8):1795-1799.
PMID: 35554520
Apolipoprotein M (apoM), primarily carried by HDL, has been associated with several conditions, including cardiovascular disease and diabetic nephropathy. This study proposes to examine whether plasma apoM levels are associated...
3.
Hammad S, Hunt K, Baker N, Klein R, Lopes-Virella M
J Clin Lipidol
. 2022 Feb;
16(2):173-183.
PMID: 35148982
Background: We have previously shown that very long ceramides/lactosylceramides predicted the development of macroalbuminuria (MA) in type 1 diabetes and expanded our studies into type 2 diabetes. Objective: This study...
4.
Semler A, Hammad S, Lopes-Virella M, Klein R, Huang Y
Neuromolecular Med
. 2021 Dec;
24(3):352-362.
PMID: 34853975
Sphingolipids are a heterogeneous class of lipids and essential components of the plasma membrane and plasma lipoproteins. Studies have shown that plasma deoxysphingolipid (DSL), a newly identified sphingolipid class, is...
5.
Hammad S, Twal W, Arif E, Semler A, Klein R, Nihalani D
Genes (Basel)
. 2020 Feb;
11(2).
PMID: 32045989
Sphingolipids are bioactive lipids associated with cellular membranes and plasma lipoproteins, and their synthesis and degradation are tightly regulated. We have previously determined that low plasma concentrations of certain ceramide...
6.
Hunt K, Jenkins A, Fu D, Stevens D, Ma J, Klein R, et al.
J Diabetes Complications
. 2019 Aug;
33(10):107410.
PMID: 31434620
Background: To determine if serum pigment epithelium-derived factor (PEDF) levels predict cardiovascular events, renal dysfunction and mortality in the Veterans Affairs Diabetes Study (VADT). Methods: PEDF was evaluated in relation...
7.
Basu A, Bebu I, Jenkins A, Stoner J, Zhang Y, Klein R, et al.
J Lipid Res
. 2019 Jun;
60(8):1432-1439.
PMID: 31203233
APOB, APOC3, and APOE and apolipoprotein-defined lipoprotein subclasses (ADLSs; based on qualitative apolipoprotein complement) have been associated with dyslipidemia and CVD. Our main objective was to define associations of serum...
8.
Lopes-Virella M, Baker N, Hunt K, Hammad S, Arthur J, Virella G, et al.
J Clin Lipidol
. 2019 May;
13(3):481-491.e1.
PMID: 31043336
Background: Glycosphingolipids are important components of cell membranes, modulators of cell-cell interactions and cell recognition, and have recently emerged as bioactive molecules and important players in nearly all cell biological...
9.
Basu A, Jenkins A, Stoner J, Zhang Y, Klein R, Lopes-Virella M, et al.
J Lipid Res
. 2018 Mar;
59(5):872-883.
PMID: 29576550
Circulating apolipoprotein-defined lipoprotein subclasses (ADLS) and apolipoproteins predict vascular events in the general and type 2 diabetes populations, but data in T1D are limited. We examined associations of ADLS, serum...
10.
Baker N, Hunt K, Stevens D, Jarai G, Rosen G, Klein R, et al.
Diabetes Care
. 2017 Nov;
41(1):128-135.
PMID: 29118060
Objective: To determine whether biomarkers of inflammation and endothelial dysfunction are associated with the development of kidney dysfunction and the time frame of their association. Research Design And Methods: Biomarkers...