Richard K Yang
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Explore the profile of Richard K Yang including associated specialties, affiliations and a list of published articles.
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38
Citations
484
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Recent Articles
1.
Gao Y, Yang R, Curry J, Torres-Cabala C, Cho W
Am J Dermatopathol
. 2025 Mar;
PMID: 40036483
B-Raf Proto-Oncogene (BRAF) fusions are rare in melanomas. We present a case of cutaneous melanoma with a Ring Finger Protein 11 (RNF11)::BRAF fusion in a 63-year-old man with a history...
2.
Lenskaya V, Yang R, Aung P, Prieto V, Nagarajan P, Cho W
Am J Dermatopathol
. 2025 Mar;
PMID: 40036479
Merkel cell carcinomas (MCCs) exhibit diverse molecular profiles, often categorized by their association with Merkel cell polyoma virus (MCPyV). MCPyV-associated MCCs typically display a low tumor mutational burden (TMB), lacking...
3.
Bowen M, Melendez B, Zhang Q, Moreno D, Peralta L, Chan W, et al.
JCI Insight
. 2025 Feb;
PMID: 39964762
Lynch syndrome (LS), caused by inherited mutations in DNA mismatch repair genes including MSH2, carries a 60% lifetime risk of developing endometrial cancer (EC). Beyond hypermutability, mechanisms driving LS-associated EC...
4.
Cazzato G, Daruish M, Fortarezza F, Colagrande A, Marzullo A, Ingravallo G, et al.
Am J Dermatopathol
. 2025 Feb;
PMID: 39912629
Gene rearrangements or fusions have emerged as critical oncogenic drivers in various cutaneous adnexal neoplasms. This review offers a comprehensive overview of both established and recently identified molecular alterations, with...
5.
Yang R, Alvarez H, Lucas A, Roy-Chowdhuri S, Rashid A, Chen H, et al.
Cancer Genet
. 2024 Dec;
290-291():44-50.
PMID: 39700818
Impairment of DNA mismatch repair function in neoplasms can be assessed by DNA-based methods to assess for high microsatellite instability (MSI-High) or immunohistochemical (IHC) analysis to assess for deficiency of...
6.
Holla V, Kahle M, Kim S, Ronaghy A, Yang R, Patel K, et al.
JCO Precis Oncol
. 2024 Nov;
8:e2400419.
PMID: 39576951
Purpose: PD-1 inhibition is effective in patients with mismatch repair deficient (dMMR) solid tumors in a tumor-agnostic fashion. However, dMMR testing by immunohistochemistry (IHC) is not routinely performed across tumor...
7.
Ibrahim E, Yang R, Curry J, Cho W
Am J Dermatopathol
. 2024 Jul;
46(11):797-799.
PMID: 39008495
No abstract available.
8.
Cho W, Prieto V, Yang R
Am J Dermatopathol
. 2024 Jun;
46(10):700-703.
PMID: 38941542
Spitz melanocytic neoplasms exhibit frequent chromosomal rearrangements leading to recurring gene fusions, such as ALK fusions. TPM3 and DCTN1 emerge as the predominant fusion partners of ALK , although less...
9.
Bowen M, Melendez B, Zhang Q, Yang R, Fellman B, Lawson B, et al.
Clin Cancer Res
. 2024 Jun;
30(22):5073-5082.
PMID: 38922360
Purpose: Nonsurgical treatment options are increasingly needed for endometrial atypical hyperplasia (AH) and endometrioid endometrial cancer (EEC). Despite promising initial response rates, prospective long-term data and determinants for relapse are...
10.
Bowen M, Melendez B, Zhang Q, Moreno D, Peralta L, Chan W, et al.
bioRxiv
. 2024 Jun;
PMID: 38915709
Significance: This is the first study to report mitochondrial dysfunction contributing to MSH2-deficient endometrial cancer development, identifying a noncanonical pathway for MSH2 deficient carcinogenesis, which also imparts vulnerability to metabolic...