Richard J White
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Explore the profile of Richard J White including associated specialties, affiliations and a list of published articles.
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51
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1271
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Recent Articles
11.
White R, Hasan S, Monga D, Finley G, Islam M, Schiffman S, et al.
Pancreas
. 2019 Aug;
48(8):1086-1091.
PMID: 31404024
Objectives: The appropriate timing of chemotherapy following surgery for resectable pancreatic adenocarcinoma is controversial. Using the National Cancer Database we evaluated time to initiation of chemotherapy postresection and correlated with...
12.
Collins J, White R, Staudt N, Sealy I, Packham I, Wali N, et al.
Nat Commun
. 2019 Jun;
10(1):2792.
PMID: 31243271
The Deciphering the Mechanisms of Developmental Disorders programme has analysed the morphological and molecular phenotypes of embryonic and perinatal lethal mouse mutant lines in order to investigate the causes of...
13.
Dooley C, Wali N, Sealy I, White R, Stemple D, Collins J, et al.
PLoS Genet
. 2019 Jun;
15(6):e1008213.
PMID: 31199790
The neural crest (NC) is a vertebrate-specific cell type that contributes to a wide range of different tissues across all three germ layers. The gene regulatory network (GRN) responsible for...
14.
Wegner R, White R, Hasan S, Raj M, Monga D, Finley G, et al.
Cancer Med
. 2019 Jun;
8(8):3855-3863.
PMID: 31173487
Importance: Primary Adenocarcinoma of the anus is a rare disease with a poor prognosis and thus tends to have a more aggressive treatment algorithm, typically involving a surgical approach. Prior...
15.
Wegner R, Abel S, Hasan S, White R, Raj M, Monga D, et al.
Am J Clin Oncol
. 2019 May;
42(6):519-526.
PMID: 31136369
Background: Anal canal squamous cell carcinoma (SCC) is managed definitively with chemoradiation, reserving surgery for salvage. The dosage of radiation has varied from 30 Gy to in excess of 60 ...
16.
Wegner R, Abel S, White R, Horne Z, Hasan S, Kirichenko A
Radiat Oncol J
. 2019 Jan;
36(4):276-284.
PMID: 30630266
Purpose: Traditionally, three-dimensional conformal radiation therapy (3D-CRT) is used for neoadjuvant chemoradiation in locally advanced rectal cancer. Intensity-modulated radiation therapy (IMRT) was later developed for more conformal dose distribution, with...
17.
Scahill C, Digby Z, Sealy I, White R, Wali N, Collins J, et al.
Wellcome Open Res
. 2018 Mar;
2:77.
PMID: 29568807
Background: Mutations in proteins involved in telomere maintenance lead to a range of human diseases, including dyskeratosis congenita, idiopathic pulmonary fibrosis and cancer. Telomerase functions to add telomeric repeats back...
18.
White R, Collins J, Sealy I, Wali N, Dooley C, Digby Z, et al.
Elife
. 2017 Nov;
6.
PMID: 29144233
We have produced an mRNA expression time course of zebrafish development across 18 time points from 1 cell to 5 days post-fertilisation sampling individual and pools of embryos. Using poly(A)...
19.
Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish
Scahill C, Digby Z, Sealy I, Wojciechowska S, White R, Collins J, et al.
PLoS Genet
. 2017 Aug;
13(8):e1006959.
PMID: 28806732
KDM2A is a histone demethylase associated with transcriptional silencing, however very little is known about its in vivo role in development and disease. Here we demonstrate that loss of the...
20.
Borgel J, Tyl M, Schiller K, Pusztai Z, Dooley C, Deng W, et al.
Nucleic Acids Res
. 2017 Feb;
45(3):1114-1129.
PMID: 28180290
Functional genomic elements are marked by characteristic DNA and histone modification signatures. How combinatorial chromatin modification states are recognized by epigenetic reader proteins and how this is linked to their...