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Richard J Weinberg

Explore the profile of Richard J Weinberg including associated specialties, affiliations and a list of published articles. Areas
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Articles 76
Citations 5227
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Recent Articles
1.
Micheva K, Simhal A, Schardt J, Smith S, Weinberg R, Owen S
bioRxiv . 2024 Dec; PMID: 39713368
The rich diversity of synapses facilitates the capacity of neural circuits to transmit, process and store information. We used multiplex super-resolution proteometric imaging through array tomography to define features of...
2.
Micheva K, Gong B, Collman F, Weinberg R, Smith S, Trimmer J, et al.
eNeuro . 2023 Nov; 10(12). PMID: 37945352
Antibody (Ab)-based imaging techniques rely on reagents whose performance may be application specific. Because commercial antibodies are validated for only a few purposes, users interested in other applications may have...
3.
Micheva K, Gong B, Collman F, Weinberg R, Smith S, Trimmer J, et al.
bioRxiv . 2023 Jul; PMID: 37425759
Antibody-based imaging techniques rely on reagents whose performance may be application-specific. Because commercial antibodies are validated for only a few purposes, users interested in other applications may have to perform...
4.
Micheva K, Weinberg R, Smith S
Science . 2020 Jul; 369(6501):253-254. PMID: 32675362
No abstract available.
5.
Schurmann B, Bermingham D, Kopeikina K, Myczek K, Yoon S, Horan K, et al.
Mol Psychiatry . 2019 Apr; 25(9):2000-2016. PMID: 30967682
Postsynaptic trafficking plays a key role in regulating synapse structure and function. While spiny excitatory synapses can be stable throughout adult life, their morphology and function is impaired in Alzheimer's...
6.
Micheva K, Chang E, Nana A, Seeley W, Ting J, Cobbs C, et al.
eNeuro . 2018 Nov; 5(5). PMID: 30406183
Numerous types of inhibitory neurons sculpt the performance of human neocortical circuits, with each type exhibiting a constellation of subcellular phenotypic features in support of its specialized functions. Axonal myelination...
7.
Burette A, Judson M, Li A, Chang E, Seeley W, Philpot B, et al.
Mol Autism . 2018 Oct; 9:54. PMID: 30364390
Background: Loss of UBE3A causes Angelman syndrome, whereas excess UBE3A activity appears to increase the risk for autism. Despite this powerful association with neurodevelopmental disorders, there is still much to...
8.
Mohan V, Wyatt E, Gotthard I, Phend K, Diestel S, Duncan B, et al.
Front Cell Neurosci . 2018 Oct; 12:346. PMID: 30356641
Neurocan is a chondroitin sulfate proteoglycan present in perineuronal nets, which are associated with closure of the critical period of synaptic plasticity. During postnatal development of the neocortex dendritic spines...
9.
Simhal A, Gong B, Trimmer J, Weinberg R, Smith S, Sapiro G, et al.
Front Neuroanat . 2018 Aug; 12:51. PMID: 30065633
Application-specific validation of antibodies is a critical prerequisite for their successful use. Here we introduce an automated framework for characterization and screening of antibodies against synaptic molecules for high-resolution immunofluorescence...
10.
Sullivan C, Gotthard I, Wyatt E, Bongu S, Mohan V, Weinberg R, et al.
Sci Rep . 2018 Apr; 8(1):6143. PMID: 29670169
Perineuronal nets (PNNs) are implicated in closure of critical periods of synaptic plasticity in the brain, but the molecular mechanisms by which PNNs regulate synapse development are obscure. A receptor...