Richard J Orton
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Explore the profile of Richard J Orton including associated specialties, affiliations and a list of published articles.
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46
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2344
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Recent Articles
1.
Modha S, Hughes J, Orton R, Lytras S
Virus Evol
. 2025 Jan;
11(1):veaf002.
PMID: 39839678
Anelloviruses are a group of small, circular, single-stranded DNA viruses that are found ubiquitously across mammalian hosts. Here, we explored a large number of publicly available human microbiome datasets and...
2.
Kamel W, Ruscica V, Embarc-Buh A, de Laurent Z, Garcia-Moreno M, Demyanenko Y, et al.
Mol Cell
. 2024 Dec;
84(24):4896-4911.e7.
PMID: 39642884
RNA is a central molecule for viruses; however, the interactions that viral RNA (vRNA) establishes with the host cell is only starting to be elucidated. Here, we determine the ribonucleoprotein...
3.
Lamb K, Luka M, Saathoff M, Orton R, Phan M, Cotten M, et al.
PLoS Comput Biol
. 2024 Jan;
20(1):e1011795.
PMID: 38271457
The COVID-19 pandemic has been characterised by sequential variant-specific waves shaped by viral, individual human and population factors. SARS-CoV-2 variants are defined by their unique combinations of mutations and there...
4.
Jones S, Tyson G, Orton R, Smollett K, Manna F, Kwok K, et al.
Viruses
. 2023 Aug;
15(8).
PMID: 37632111
Although domestic cats are susceptible to infection with SARS-CoV-2, the role of the virus in causing feline disease is less well defined. We conducted a large-scale study to identify SARS-CoV-2...
5.
Li K, Lau B, Suarez N, Camiolo S, Gunson R, Davison A, et al.
Viruses
. 2023 Jun;
15(6.
PMID: 37376548
Nanopore sequencing is becoming increasingly commonplace in clinical settings, particularly for diagnostic assessments and outbreak investigations, due to its portability, low cost, and ability to operate in near real-time. Although...
6.
Johnson P, Hagglund S, Naslund K, Meyer G, Taylor G, Orton R, et al.
Vet Res
. 2022 Dec;
53(1):107.
PMID: 36510312
Bovine respiratory syncytial virus (BRSV) is a major cause of respiratory disease in cattle. Genomic sequencing can resolve phylogenetic relationships between virus populations, which can be used to infer transmission...
7.
Walker P, Siddell S, Lefkowitz E, Mushegian A, Adriaenssens E, Alfenas-Zerbini P, et al.
Arch Virol
. 2022 Aug;
167(11):2429-2440.
PMID: 35999326
This article reports the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses (ICTV) in March 2022. The entire ICTV was invited to vote...
8.
Martin D, Lytras S, Lucaci A, Maier W, Gruning B, Shank S, et al.
Mol Biol Evol
. 2022 Mar;
39(4).
PMID: 35325204
Among the 30 nonsynonymous nucleotide substitutions in the Omicron S-gene are 13 that have only rarely been seen in other SARS-CoV-2 sequences. These mutations cluster within three functionally important regions...
9.
Modha S, Robertson D, Hughes J, Orton R
mSystems
. 2022 Mar;
7(2):e0146821.
PMID: 35258340
Advances in genome sequencing technologies and lower costs have enabled the exploration of a multitude of known and novel environments and microbiomes. This has led to an exponential growth in...
10.
Martin D, Lytras S, Lucaci A, Maier W, Gruning B, Shank S, et al.
bioRxiv
. 2022 Jan;
PMID: 35075456
Among the 30 non-synonymous nucleotide substitutions in the Omicron S-gene are 13 that have only rarely been seen in other SARS-CoV-2 sequences. These mutations cluster within three functionally important regions...