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Richard J Gilbert

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Articles 49
Citations 597
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Recent Articles
1.
Leary O, Zepecki J, Pizzagalli M, Toms S, Liu D, Suita Y, et al.
Cancers (Basel) . 2024 Nov; 16(21). PMID: 39518107
Background: The invasion of glioblastoma cells beyond the visible tumor margin depicted by conventional neuroimaging is believed to mediate recurrence and predict poor survival. Radiomic biomarkers that are associated with...
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Siamwala J, Pagano F, Dubielecka P, Ivey M, Guirao-Abad J, Zhao A, et al.
Commun Biol . 2023 Nov; 6(1):1200. PMID: 38001239
The source and roles of fibroblasts and T-cells during maladaptive remodeling and myocardial fibrosis in the setting of pulmonary arterial hypertension (PAH) have been long debated. We demonstrate, using single-cell...
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Taylor E, Ding Y, Lin L, Aninwene 2nd G, Hoffman M, Fuller C, et al.
Proc IEEE Annu Northeast Bioeng Conf . 2023 May; 2015. PMID: 37256020
Current approaches for studying tumor activity in patients involve molecular characterization in excised tissue or biopsied samples. Recognizing that tumors are composed of heterogeneous arrays of cells and their environment,...
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Gilbert R, Siamwala J, Kumar V, Thompson C, Shikora S
Curr Gastroenterol Rep . 2023 Apr; 25(4):75-90. PMID: 37004633
Purpose Of Review: Gastroparesis is a chronic disorder characterized by a constellation of foregut symptoms, including postprandial nausea, vomiting, distension, epigastric pain, and regurgitation in the absence of gastric outlet...
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Mendiola E, Da Silva Goncalves Bos D, Leichter D, Vang A, Zhang P, Leary O, et al.
Circ Heart Fail . 2023 Feb; 16(2):e009768. PMID: 36748476
Background: Global indices of right ventricle (RV) function provide limited insights into mechanisms underlying RV remodeling in pulmonary hypertension (PH). While RV myocardial architectural remodeling has been observed in PH,...
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Taylor E, Huang N, Lin S, Mortazavi F, Wedeen V, Siamwala J, et al.
J Cardiovasc Magn Reson . 2022 Dec; 24(1):74. PMID: 36544161
Background: Atherosclerosis is an arterial vessel wall disease characterized by slow, progressive lipid accumulation, smooth muscle disorganization, and inflammatory infiltration. Atherosclerosis often remains subclinical until extensive inflammatory injury promotes vulnerability...
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Leichter D, Stark N, Leary O, Brodsky M, Gilbert R, Nicosia M
Comput Biol Med . 2022 Apr; 145:105446. PMID: 35390748
Biomechanical relationships involving lingual myoanatomy, contractility, and bolus movement are fundamental properties of human swallowing. To portray the relationship between lingual deformation and bolus flow during swallowing, a weakly one-way...
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Lynch 4th T, Kumar M, McNamara J, Kuster D, Sivaguru M, Singh R, et al.
J Mol Cell Cardiol . 2021 Mar; 156:33-44. PMID: 33781820
Phosphorylation of cardiac myosin binding protein-C (cMyBP-C) regulates cardiac contraction through modulation of actomyosin interactions mediated by the protein's amino terminal (N')-region (C0-C2 domains, 358 amino acids). On the other...
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Siamwala J, Zhao A, Barthel H, Pagano F, Gilbert R, Rounds S
Physiol Rep . 2020 Aug; 8(15):e14532. PMID: 32786064
Pulmonary arterial hypertension (PAH) is a syndrome diagnosed by increased mean pulmonary artery (PA) pressure and resistance and normal pulmonary capillary wedge pressure. PAH is characterized pathologically by distal pulmonary...