Richard Huganir
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Explore the profile of Richard Huganir including associated specialties, affiliations and a list of published articles.
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21
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1051
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Recent Articles
11.
Sheng M, Malinow R, Huganir R
Nature
. 2013 Jan;
493(7433):482-3.
PMID: 23344353
No abstract available.
12.
Fouillade C, Baron-Menguy C, Domenga-Denier V, Thibault C, Takamiya K, Huganir R, et al.
Arterioscler Thromb Vasc Biol
. 2012 Nov;
33(1):76-86.
PMID: 23117660
Objective: Notch3 is critically important for the structure and myogenic response of distal arteries, particularly of cerebral arteries. However, signaling pathways acting downstream of Notch3 remain largely unknown. Methods And...
13.
Huang S, Trevino M, He K, Ardiles A, de Pasquale R, Guo Y, et al.
Neuron
. 2012 Feb;
73(3):497-510.
PMID: 22325202
Neuromodulatory input, acting on G protein-coupled receptors, is essential for the induction of experience-dependent cortical plasticity. Here we report that G-coupled receptors in layer II/III of visual cortex control the...
14.
Kristensen A, Jenkins M, Banke T, Schousboe A, Makino Y, Johnson R, et al.
Nat Neurosci
. 2011 Apr;
14(6):727-35.
PMID: 21516102
The function, trafficking and synaptic signaling of AMPA receptors are tightly regulated by phosphorylation. Ca(2+)/calmodulin-dependent kinase II (CaMKII) phosphorylates the GluA1 AMPA receptor subunit at Ser831 to increase single-channel conductance....
15.
Thorsen T, Madsen K, Rebola N, Rathje M, Anggono V, Bach A, et al.
Proc Natl Acad Sci U S A
. 2009 Dec;
107(1):413-8.
PMID: 20018661
Proteins containing PSD-95/Discs-large/ZO-1 homology (PDZ) domains play key roles in the assembly and regulation of cellular signaling pathways and represent putative targets for new pharmacotherapeutics. Here we describe the first...
16.
Zhou W, Zhang L, Guoxiang X, Mojsilovic-Petrovic J, Takamaya K, Sattler R, et al.
J Neurosci
. 2008 Oct;
28(41):10220-33.
PMID: 18842882
Activity-dependent dendrite elaboration influences the pattern of interneuronal connectivity and network function. In the present study, we examined the mechanism by which the GluR1 subunit of AMPA receptors controls dendrite...
17.
Szklarczyk A, Ewaleifoh O, Beique J, Wang Y, Knorr D, Haughey N, et al.
FASEB J
. 2008 Jul;
22(11):3757-67.
PMID: 18644839
Matrix metalloproteinases (MMPs) are zinc-dependent enzymes that play a role in the inflammatory response. These enzymes have been well studied in the context of cancer biology and inflammation. Recent studies,...
18.
Morrell C, Sun H, Ikeda M, Beique J, Swaim A, Mason E, et al.
J Exp Med
. 2008 Feb;
205(3):575-84.
PMID: 18283118
Glutamate is an excitatory neurotransmitter that binds to the kainate receptor, the N-methyl-D-aspartate (NMDA) receptor, and the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor (AMPAR). Each receptor was first characterized and cloned in...
19.
Kim C, Takamiya K, Petralia R, Sattler R, Yu S, Zhou W, et al.
Nat Neurosci
. 2005 Jul;
8(8):985-7.
PMID: 16007085
The C-terminal PDZ ligand of the AMPA receptor GluR1 subunit may be important for expression of CA1 hippocampal long-term potentiation. To test this directly in vivo, we generated a knock-in...
20.
Lin H, Huganir R, Liao D
Biochem Biophys Res Commun
. 2004 Mar;
316(2):501-11.
PMID: 15020245
Recent studies have shown that the activation of NMDA receptors can induce rapid changes in dendritic morphology and synaptic recruitment of AMPA receptors in dendritic spines. Here, we analyze the...