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Richard Furman

Explore the profile of Richard Furman including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 1095
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Recent Articles
11.
Dubovsky J, Beckwith K, Natarajan G, Woyach J, Jaglowski S, Zhong Y, et al.
Blood . 2013 Jul; 122(15):2539-49. PMID: 23886836
Given its critical role in T-cell signaling, interleukin-2-inducible kinase (ITK) is an appealing therapeutic target that can contribute to the pathogenesis of certain infectious, autoimmune, and neoplastic diseases. Ablation of...
12.
OConnor O, Pro B, Pinter-Brown L, Bartlett N, Popplewell L, Coiffier B, et al.
J Clin Oncol . 2011 Jan; 29(9):1182-9. PMID: 21245435
Purpose: Peripheral T-cell lymphoma (PTCL) is a poor prognosis subtype of non-Hodgkin's lymphoma with no accepted standard of care. This study evaluated the efficacy and tolerability of pralatrexate, a novel...
13.
van Rhee F, Fayad L, Voorhees P, Furman R, Lonial S, Borghaei H, et al.
J Clin Oncol . 2010 Jul; 28(23):3701-8. PMID: 20625121
Purpose: Interleukin-6 (IL-6) has emerged as a key factor in the pathogenesis of the atypical lymphoproliferative disorder Castleman's disease (CD). Siltuximab is a new anti-IL-6, chimeric monoclonal antibody with potential...
14.
Elstrom R, Martin P, Ostrow K, Barrientos J, Chadburn A, Furman R, et al.
Clin Lymphoma Myeloma Leuk . 2010 Jun; 10(3):192-6. PMID: 20511164
Background: Patients with diffuse large B-cell lymphoma (DLBCL) who are not cured by initial therapy sometimes experience disease-free survival after autologous stem cell transplantation. Chemotherapy responsiveness before transplantation is a...
15.
Coleman M, Martin P, Ruan J, Furman R, Niesvizky R, Elstrom R, et al.
Cancer . 2008 Mar; 112(10):2228-32. PMID: 18338745
Background: Many patients with recurrent lymphoma are unable to tolerate intensive therapies, or have disease that is refractory. Metronomic chemotherapy offers a novel, potentially less toxic yet effective treatment strategy....
16.
Coleman M, Martin P, Ruan J, Furman R, Niesvizky R, Elstrom R, et al.
Leuk Lymphoma . 2008 Feb; 49(3):447-50. PMID: 18297520
The prednisone, etoposide, procarbazine and cyclophosphamide (PEP-C) oral combination chemotherapy regimen (prednisone 20 mg, cyclophosphamide 50 mg, etoposide 50 mg, and procarbazine 50 mg with an oral anti-emetic) was employed...
17.
Leonard J, Coleman M, Ketas J, Chadburn A, Furman R, Schuster M, et al.
Clin Cancer Res . 2004 Aug; 10(16):5327-34. PMID: 15328168
Purpose: We conducted a single-center, dose-escalation study evaluating the safety, pharmacokinetics, and efficacy of epratuzumab, an anti-CD22 humanized monoclonal antibody, in patients with aggressive non-Hodgkin's lymphoma. Experimental Design: Epratuzumab was...