Richard F Murphy
Overview
Explore the profile of Richard F Murphy including associated specialties, affiliations and a list of published articles.
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40
Citations
481
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Recent Articles
1.
Palermo N, Thomas P, Murphy R, Lovas S
J Pept Sci
. 2012 Mar;
18(4):252-60.
PMID: 22392880
Colorectal cancers with metastatic potential secrete the glycoprotein carcinoembryonic antigen (CEA). CEA has been implicated in colorectal cancer metastasis by inducing Kupffer cells to produce inflammatory cytokines which, in turn,...
2.
Hatfield M, Murphy R, Lovas S
J Phys Chem B
. 2011 Apr;
115(17):4971-81.
PMID: 21480621
The conformational stability of the β-hairpin miniprotein, CLN025, a variant of chignolin in which the N- and C-terminal glycines are replaced by tyrosines, in various concentrations of guanidinium chloride (GdmCl)...
3.
Aggarwal A, Hunter 3rd W, Aggarwal H, Silva E, Davey M, Murphy R, et al.
Exp Mol Pathol
. 2010 May;
89(2):140-8.
PMID: 20471975
The POK family of proteins plays an important role in not only embryonic development and cell differentiation, but also in oncogenesis. Leukemia/lymphoma-related factor (LRF) belongs to the POK family of...
4.
Hatfield M, Murphy R, Lovas S
J Phys Chem B
. 2010 Feb;
114(8):3028-37.
PMID: 20148510
Molecular dynamics simulations of a beta-hairpin miniprotein, CLN025, were performed to examine the conformational stability of the peptide in H(2)O at 278, 300, 333, and 363 K, as well as...
5.
Copps J, Murphy R, Lovas S
Protein Pept Lett
. 2009 Dec;
16(12):1504-18.
PMID: 20001914
The gastrointestinal peptide hormone gastrin is responsible for initiating the release of gastric acid in the stomach in response to the presence of food and/or humoral factors such as gastrin...
6.
Hatfield M, Murphy R, Lovas S
Biopolymers
. 2009 Nov;
93(5):442-50.
PMID: 19937759
Electronic and vibrational circular dichroism are often used to determine the secondary structure of proteins, because each secondary structure has a unique spectrum. Little is known about the vibrational circular...
7.
Copps J, Murphy R, Lovas S
Peptides
. 2009 Sep;
30(12):2250-62.
PMID: 19766682
Gastrin-17 (G17) processing intermediates bind to non-CCK receptors which mediate growth of the colonic mucosa but also the formation and development of colonic cancers. In previous studies, we removed the...
8.
Copps J, Ahmed S, Murphy R, Lovas S
Peptides
. 2009 Sep;
30(12):2263-7.
PMID: 19761808
Gastrin-17-Gly (G17-Gly) has been shown to bind to non-CCK nanomolar and micromolar affinity sites on DLD-1 and HT-29 human colonic carcinoma cells and to stimulate cellular proliferation. However, in previous...
9.
Palermo N, Csontos J, Murphy R, Lovas S
Adv Exp Med Biol
. 2009 Apr;
611:89-90.
PMID: 19400107
No abstract available.
10.
Csontos J, Murphy R, Lovas S
Adv Exp Med Biol
. 2009 Apr;
611:79-80.
PMID: 19400102
No abstract available.