Richard E Sutton
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Explore the profile of Richard E Sutton including associated specialties, affiliations and a list of published articles.
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51
Citations
868
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Recent Articles
11.
Zhao M, Su P, Castro D, Tripler T, Hu Y, Cook M, et al.
PLoS Pathog
. 2021 Jun;
17(6):e1009683.
PMID: 34166473
COVID-19 is a global crisis of unimagined dimensions. Currently, Remedesivir is only fully licensed FDA therapeutic. A major target of the vaccine effort is the SARS-CoV-2 spike-hACE2 interaction, and assessment...
12.
Gonzalo-Gil E, Rapuano P, Ikediobi U, Leibowitz R, Mehta S, Coskun A, et al.
Elife
. 2019 Apr;
8.
PMID: 30964004
HIV +Elite and Viremic controllers (EC/VCs) are able to control virus infection, perhaps because of host genetic determinants. We identified 16% (21 of 131) EC/VCs with CD4 +T cells with...
13.
Zhang Y, Chapman J, Ulcay A, Sutton R
J Virol
. 2018 Dec;
93(4).
PMID: 30518644
Attachment inhibitor (AI) BMS-626529 (fostemsavir) represents a novel class of antiretrovirals which target human immunodeficiency virus type 1 (HIV-1) gp120 and block CD4-induced conformational changes required for viral entry. It...
14.
Kayongo A, Gonzalo-Gil E, Gumusgoz E, Niwaha A, Semitala F, Kalyesubula R, et al.
J Acquir Immune Defic Syndr
. 2018 Aug;
79(3):394-398.
PMID: 30063647
Background: Throughout the world, there are antiretroviral therapy-naive HIV+ individuals who maintain elevated peripheral CD4 T-cell counts, historically referred to as long-term nonprogressors (LTNPs). With recent improvements in viral load...
15.
Yue Y, Coskun A, Jawanda N, Auer J, Sutton R
Virology
. 2017 Oct;
513:1-10.
PMID: 29028476
Mice have multiple obstacles to HIV replication, including a block of unspliced and partially spliced viral mRNA nuclear export. In human, Rev binds to the Rev-response element and human (h)...
16.
Gonzalo-Gil E, Ikediobi U, Sutton R
Yale J Biol Med
. 2017 Jun;
90(2):245-259.
PMID: 28656011
Human immunodeficiency virus type 1 (HIV-1) disease is pandemic, with approximately 36 million infected individuals world-wide. For the vast majority of these individuals, untreated HIV eventually causes CD4+ T cell...
17.
Ikediobi U, Sutton R
JMM Case Rep
. 2017 Mar;
3(1):e005018.
PMID: 28348749
Introduction: Fungal endocarditis is a rare cause of infective endocarditis, and spp. account for up to 30 % of all cases. Risk factors include intravenous drug use, immunosuppression, malignancy and...
18.
Hu Y, OBoyle K, Auer J, Raju S, You F, Wang P, et al.
PLoS Pathog
. 2017 Feb;
13(2):e1006187.
PMID: 28152074
UBXN proteins likely participate in the global regulation of protein turnover, and we have shown that UBXN1 interferes with RIG-I-like receptor (RLR) signaling by interacting with MAVS and impeding its...
19.
Zhang X, Justice A, Hu Y, Wang Z, Zhao H, Wang G, et al.
Epigenetics
. 2016 Sep;
11(10):750-760.
PMID: 27672717
Epigenetic control of human immunodeficiency virus-1 (HIV-1) genes is critical for viral integration and latency. However, epigenetic changes in the HIV-1-infected host genome have not been well characterized. Here, we...
20.