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Richard D Grieve

Explore the profile of Richard D Grieve including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 1093
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Recent Articles
1.
Richards-Belle A, Mouncey P, Grieve R, Harrison D, Zia Sadique M, Henry D, et al.
J Intensive Care Soc . 2021 Jun; 21(4):281-282. PMID: 34093727
Vasodilatory shock is common in critically ill patients and vasopressors are a mainstay of therapy. A meta-analysis suggested that use of a higher, as opposed to a lower, mean arterial...
2.
Mouncey P, Richards-Belle A, Thomas K, Harrison D, Zia Sadique M, Grieve R, et al.
Health Technol Assess . 2021 Mar; 25(14):1-90. PMID: 33648623
Background: Vasopressors are administered to critical care patients to avoid hypotension, which is associated with myocardial injury, kidney injury and death. However, they work by causing vasoconstriction, which may reduce...
3.
Thomas K, Patel A, Zia Sadique M, Grieve R, Mason A, Moler S, et al.
J Intensive Care Soc . 2020 Aug; 21(3):230-231. PMID: 32782462
The 65 trial is a pragmatic, multicentre, parallel-group, open-label, randomised clinical trial of permissive hypotension (targeting a mean arterial pressure target of 60-65 mmHg during vasopressor therapy) versus usual care...
4.
Mason A, Grieve R, Richards-Belle A, Mouncey P, Harrison D, Carpenter J
BMC Med Res Methodol . 2020 Mar; 20(1):66. PMID: 32183708
Background: Missing data are an inevitable challenge in Randomised Controlled Trials (RCTs), particularly those with Patient Reported Outcome Measures. Methodological guidance suggests that to avoid incorrect conclusions, studies should undertake...
5.
Lamontagne F, Richards-Belle A, Thomas K, Harrison D, Zia Sadique M, Grieve R, et al.
JAMA . 2020 Feb; 323(10):938-949. PMID: 32049269
Importance: Vasopressors are commonly administered to intensive care unit (ICU) patients to raise blood pressure. Balancing risks and benefits of vasopressors is a challenge, particularly in older patients. Objective: To...
6.
Wade D, Mouncey P, Richards-Belle A, Wulff J, Harrison D, Zia Sadique M, et al.
JAMA . 2019 Feb; 321(7):665-675. PMID: 30776295
Importance: A meta-analysis of outcomes during the 6 months after intensive care unit (ICU) discharge indicate a prevalence for clinically important posttraumatic stress disorder (PTSD) symptoms of 25%. Objective: To...
7.
Rowan K, Angus D, Bailey M, Barnato A, Bellomo R, Canter R, et al.
N Engl J Med . 2017 Mar; 376(23):2223-2234. PMID: 28320242
Background: After a single-center trial and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality from septic shock, three multicenter trials (ProCESS, ARISE, and ProMISe) showed no benefit. This...
8.
Harvey S, Parrott F, Harrison D, Zia Sadique M, Grieve R, Canter R, et al.
Health Technol Assess . 2016 Apr; 20(28):1-144. PMID: 27089843
Background: Malnutrition is a common problem in critically ill patients in UK NHS critical care units. Early nutritional support is therefore recommended to address deficiencies in nutritional state and related...
9.
Mouncey P, Osborn T, Sarah Power G, Harrison D, Zia Sadique M, Grieve R, et al.
Health Technol Assess . 2015 Nov; 19(97):i-xxv, 1-150. PMID: 26597979
Background: Early goal-directed therapy (EGDT) is recommended in international guidance for the resuscitation of patients presenting with early septic shock. However, adoption has been limited and uncertainty remains over its...
10.
Mouncey P, Osborn T, Sarah Power G, Harrison D, Zia Sadique M, Grieve R, et al.
N Engl J Med . 2015 Mar; 372(14):1301-11. PMID: 25776532
Background: Early, goal-directed therapy (EGDT) is recommended in international guidelines for the resuscitation of patients presenting with early septic shock. However, adoption has been limited, and uncertainty about its effectiveness...