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Richard Chen

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Articles 94
Citations 1992
Followers 0
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Recent Articles
11.
Puri S, Maachi H, Nair G, Russ H, Chen R, Pulimeno P, et al.
Nat Commun . 2024 Jan; 15(1):588. PMID: 38238288
Despite significant research, mechanisms underlying the failure of islet beta cells that result in type 2 diabetes (T2D) are still under investigation. Here, we report that Sox9, a transcriptional regulator...
12.
Briere R, Emond M, Benhamed A, Blanchard P, Golbon B, Shellenberger J, et al.
Can J Surg . 2024 Jan; 66(6 Suppl 1):S54-S136. PMID: 38173057
No abstract available.
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Chen T, Chen R, You A, Kouznetsova V, Tsigelny I
Adv Ophthalmol Pract Res . 2023 Nov; 3(4):187-191. PMID: 37928946
Purpose: Patients with diabetes mellitus have an elevated chance of developing cataracts, a degenerative vision-impairing condition often needing surgery. The process of the reduction of glucose to sorbitol in the...
15.
Harpel Z, Chang W, Circelli J, Chen R, Chang I, Rivera J, et al.
PLoS One . 2023 Sep; 18(9):e0284309. PMID: 37708236
Tetrahymena are ciliated protists that have been used to study the effects of toxic chemicals, including anticancer drugs. In this study, we tested the inhibitory effects of six pyrimidine analogs...
16.
Saldivar J, Harris J, Ayash E, Hong M, Tandon P, Sinha S, et al.
Oncotarget . 2023 Aug; 14:789-806. PMID: 37646774
We describe the analytic validation of NeXT Dx, a comprehensive genomic profiling assay to aid therapy and clinical trial selection for patients diagnosed with solid tumor cancers. Proprietary methods were...
17.
Modi K, Chen R, Abubshait L
Clin Pract Cases Emerg Med . 2023 Aug; 7(3):202-204. PMID: 37595298
Case Presentation: Early diagnosis and rapid treatment of cancer is essential for good clinical outcomes for patients. In this case, an 85-year-old man presented with failure to thrive and was...
18.
Pyke R, Mellacheruvu D, Dea S, Abbott C, Zhang S, Phillips N, et al.
Mol Cell Proteomics . 2023 Apr; 22(4):100511. PMID: 37019059
No abstract available.
19.
Pyke R, Mellacheruvu D, Dea S, Abbott C, Zhang S, Phillips N, et al.
Mol Cell Proteomics . 2023 Feb; 22(4):100506. PMID: 36796642
Major histocompatibility complex (MHC)-bound peptides that originate from tumor-specific genetic alterations, known as neoantigens, are an important class of anticancer therapeutic targets. Accurately predicting peptide presentation by MHC complexes is...
20.
Suppes T, Durgam S, Kozauer S, Chen R, Lakkis H, Davis R, et al.
Bipolar Disord . 2023 Feb; 25(6):478-488. PMID: 36779257
Objective: This phase 3, randomized, double-blind, placebo-controlled study (NCT02600507) evaluated the efficacy and safety of lumateperone adjunctive therapy to lithium or valproate in patients with bipolar depression. Methods: Patients (18-75 ...