Richard C Condit
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Explore the profile of Richard C Condit including associated specialties, affiliations and a list of published articles.
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Citations
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Recent Articles
11.
Condit R, Williamson A, Sheets R, Seligman S, P Monath T, Excler J, et al.
Vaccine
. 2016 Jun;
34(51):6610-6616.
PMID: 27346303
In 2003 and 2013, the World Health Organization convened informal consultations on characterization and quality aspects of vaccines based on live virus vectors. In the resulting reports, one of several...
12.
Klug B, Robertson J, Condit R, Seligman S, Laderoute M, Sheets R, et al.
Vaccine
. 2016 Jun;
34(51):6617-6625.
PMID: 27317264
Vaccines are one of the most effective public health medicinal products with an excellent safety record. As vaccines are produced using biological materials, there is a need to safeguard against...
13.
Jesus D, Moussatche N, Condit R
J Struct Biol
. 2016 May;
195(1):41-8.
PMID: 27155322
In recent years, high pressure freezing and freeze substitution have been widely used for electron microscopy to reveal viral and cellular structures that are difficult to preserve. Vaccinia virus, a...
14.
Tate J, Boldt R, McFadden B, DCosta S, Lewandowski N, Shatzer A, et al.
Virology
. 2015 Oct;
487:27-40.
PMID: 26496697
Prior biochemical analysis of the heterodimeric vaccinia virus mRNA capping enzyme suggests roles not only in mRNA capping but also in early viral gene transcription termination and intermediate viral gene...
15.
Condit R, Moussatche N
Virology
. 2015 Apr;
482:147-56.
PMID: 25863879
Vaccinia virus mutants in which expression of the virion core protein gene E6R is repressed are defective in virion morphogenesis. E6 deficient infections fail to properly package viroplasm into viral...
16.
Jesus D, Moussatche N, McFadden B, Nielsen C, DCosta S, Condit R
Virology
. 2015 Mar;
481:1-12.
PMID: 25765002
Maturation of the vaccinia virion is an intricate process that results in the organization of the viroplasm contained in immature virions into the lateral bodies, core wall and nucleocapsid observed...
17.
Moussatche N, Condit R
Virology
. 2014 Dec;
475:204-18.
PMID: 25486587
The vaccinia virion is a membraned, slightly flattened, barrel-shaped particle, with a complex internal structure featuring a biconcave core flanked by lateral bodies. Although the architecture of the purified mature...
18.
P Monath T, Seligman S, Robertson J, Guy B, Hayes E, Condit R, et al.
Vaccine
. 2014 Dec;
33(1):62-72.
PMID: 25446819
The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) was formed to evaluate the safety of live, recombinant viral vaccines incorporating genes from heterologous viruses inserted into the backbone...
19.
Chen R, Carbery B, Mac L, Berns K, Chapman L, Condit R, et al.
Vaccine
. 2014 Oct;
33(1):73-5.
PMID: 25305565
Recombinant viral vectors provide an effective means for heterologous antigen expression in vivo and thus represent promising platforms for developing novel vaccines against human pathogens from Ebola to tuberculosis. An...
20.
Jesus D, Moussatche N, Condit R
J Virol
. 2014 Sep;
88(24):14017-29.
PMID: 25253347
Unlabelled: Electron micrographs from the 1960s revealed the presence of an S-shaped tubular structure in the center of the vaccinia virion core. Recently, we showed that packaging of virus transcription...