Rianne van den Helder
Overview
Explore the profile of Rianne van den Helder including associated specialties, affiliations and a list of published articles.
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9
Citations
81
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Recent Articles
1.
Schaafsma M, van den Helder R, Mom C, Steenbergen R, Bleeker M, van Trommel N
Int J Cancer
. 2024 Aug;
156(3):659-667.
PMID: 39175103
Early detection of recurrent cervical cancer is important to improve survival rates. The aim of this study was to explore the clinical performance of DNA methylation markers and high-risk human...
2.
Wever B, Schaafsma M, Bleeker M, van den Burgt Y, van den Helder R, Lok C, et al.
Commun Med (Lond)
. 2024 May;
4(1):88.
PMID: 38755429
Background: High ovarian cancer mortality rates motivate the development of effective and patient-friendly diagnostics. Here, we explored the potential of molecular testing in patient-friendly samples for ovarian cancer detection. Methods:...
3.
Wever B, van den Helder R, van Splunter A, van Gent M, Kasius J, Trum J, et al.
Int J Cancer
. 2023 Mar;
153(2):341-351.
PMID: 36912267
Endometrial cancer incidence is rising and current diagnostics often require invasive biopsy procedures. DNA methylation marker analysis of minimally- and non-invasive sample types could provide an easy-to-apply and patient-friendly alternative...
4.
van den Helder R, Steenbergen R, van Splunter A, Mom C, Tjiong M, Martin I, et al.
Clin Cancer Res
. 2022 Mar;
28(10):2061-2068.
PMID: 35266975
Purpose: Biomarker detection in urine offers a potential solution to increase effectiveness of cervical cancer screening programs by attracting nonresponders. In this prospective study, the presence of high-risk human papillomavirus...
5.
Schaafsma M, van den Helder R, Bleeker M, Rosier-van Dunne F, van der Avoort I, Steenbergen R, et al.
Prev Med Rep
. 2022 Mar;
26:101749.
PMID: 35256928
The effectiveness of cervical cancer screening is hampered by low attendance rates. The collection of a urine sample is hypothesized to engage non-attenders in cervical cancer screening. The aim of...
6.
Hentschel A, van den Helder R, van Trommel N, van Splunter A, van Boerdonk R, van Gent M, et al.
Cancers (Basel)
. 2021 Feb;
13(3).
PMID: 33572525
In urogenital cancers, urine as a liquid biopsy for non-invasive cancer detection holds great promise for future clinical application. Their anatomical position allows for the local shedding of tumor DNA,...
7.
van den Helder R, Wever B, van Trommel N, van Splunter A, Mom C, Kasius J, et al.
Clin Epigenetics
. 2020 Nov;
12(1):165.
PMID: 33143739
Background: The incidence of endometrial cancer is rising, and current diagnostics often require invasive biopsy procedures. Urine may offer an alternative sample type, which is easily accessible and allows repetitive...
8.
van den Helder R, Wever B, van Trommel J, Ket J, Bleeker M, Steenbergen R, et al.
Epigenomics
. 2020 Sep;
12(18):1661-1672.
PMID: 32938224
DNA methylation testing for endometrial cancer detection in minimally invasive specimens is a promising tool to improve screening and diagnostic procedures. Available literature was systematically reviewed to assess the potential...
9.
van den Helder R, van Trommel N, van Splunter A, Lissenberg-Witte B, Bleeker M, Steenbergen R
Papillomavirus Res
. 2020 Mar;
9:100193.
PMID: 32171935
Introduction: Urine sampling is an interesting solution for CIN3 and cervical cancer detection. Urine can be separated in different fractions: full void urine, urine sediment and urine supernatant. We aimed...