Ria Roelandt
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Explore the profile of Ria Roelandt including associated specialties, affiliations and a list of published articles.
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22
Citations
1212
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Recent Articles
1.
Ruiz Perez M, Maueroder C, Steels W, Verstraeten B, Lameire S, Xie W, et al.
Cell Mol Immunol
. 2024 Jun;
21(8):807-825.
PMID: 38839915
Acute systemic inflammation critically alters the function of the immune system, often promoting myelopoiesis at the expense of lymphopoiesis. In the thymus, systemic inflammation results in acute thymic atrophy and,...
2.
Ingels J, De Cock L, Stevens D, Mayer R, Thery F, Sanchez Sanchez G, et al.
Cell Rep Med
. 2024 Apr;
5(5):101516.
PMID: 38626769
Non-small cell lung cancer (NSCLC) is known for high relapse rates despite resection in early stages. Here, we present the results of a phase I clinical trial in which a...
3.
Tougaard P, Ruiz Perez M, Steels W, Huysentruyt J, Verstraeten B, Vetters J, et al.
Sci Adv
. 2024 Jan;
10(3):eadh5520.
PMID: 38232171
Acute thymic atrophy occurs following type 1 inflammatory conditions such as viral infection and sepsis, resulting in cell death and disruption of T cell development. However, the impact type 1...
4.
Peleman C, Van Coillie S, Ligthart S, Choi S, De Waele J, Depuydt P, et al.
Cell Death Differ
. 2023 Aug;
30(9):2066-2077.
PMID: 37582864
Critical COVID-19 patients admitted to the intensive care unit (ICU) frequently suffer from severe multiple organ dysfunction with underlying widespread cell death. Ferroptosis and pyroptosis are two detrimental forms of...
5.
Bosteels V, Marechal S, De Nolf C, Rennen S, Maelfait J, Tavernier S, et al.
Sci Immunol
. 2023 May;
8(83):eadd3955.
PMID: 37172103
Dendritic cells (DCs) mature in an immunogenic or tolerogenic manner depending on the context in which an antigen is perceived, preserving the balance between immunity and tolerance. Whereas the pathways...
6.
Van Coillie S, Van San E, Goetschalckx I, Wiernicki B, Mukhopadhyay B, Tonnus W, et al.
Nat Commun
. 2022 Feb;
13(1):1046.
PMID: 35210435
The most common cause of death in the intensive care unit (ICU) is the development of multiorgan dysfunction syndrome (MODS). Besides life-supporting treatments, no cure exists, and its mechanisms are...
7.
Ghazavi F, Huysentruyt J, De Coninck J, Kourula S, Martens S, Hassannia B, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(6).
PMID: 35105800
Apoptosis is widely believed to be crucial for epithelial cell death and shedding in the intestine, thereby shaping the overall architecture of the gastrointestinal tract, but also regulating tolerance induction,...
8.
Martens S, Bridelance J, Roelandt R, Vandenabeele P, Takahashi N
Cell Death Differ
. 2021 May;
28(6):1757-1772.
PMID: 33953348
Mixed lineage kinase domain-like protein (MLKL) emerged as executioner of necroptosis, a RIPK3-dependent form of regulated necrosis. Cell death evasion is one of the hallmarks of cancer. Besides apoptosis, some...
9.
De Schutter E, Roelandt R, Riquet F, Van Camp G, Wullaert A, Vandenabeele P
Trends Cell Biol
. 2021 Mar;
31(6):500-513.
PMID: 33771452
The gasdermin (GSDM) family has evolved as six gene clusters (GSDMA-E and Pejvakin, PJVK), and GSDM proteins are characterized by a unique N-terminal domain (N-GSDM). With the exception of PJVK,...
10.
Hoste E, Maueroder C, Van Hove L, Catrysse L, Vikkula H, Sze M, et al.
Cell Rep
. 2019 Nov;
29(9):2689-2701.e4.
PMID: 31775038
Regenerative responses predispose tissues to tumor formation by largely unknown mechanisms. High-mobility group box 1 (HMGB1) is a danger-associated molecular pattern contributing to inflammatory pathologies. We show that HMGB1 derived...