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Rhiannon R Penkert

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Recent Articles
11.
Penkert R, Vargas E, Prehoda K
J Biol Chem . 2022 Jul; 298(8):102223. PMID: 35787373
The animal cell polarity regulator Par-3 recruits the Par complex (consisting of Par-6 and atypical PKC, aPKC) to specific sites on the cell membrane. Although numerous physical interactions have been...
12.
Penkert R, Chandramouli S, Dormitzer P, Settembre E, Sealy R, Wong S, et al.
Vaccines (Basel) . 2021 Aug; 9(8). PMID: 34451986
Children with sickle cell disease (SCD) suffer life-threatening transient aplastic crisis (TAC) when infected with parvovirus B19. In utero, infection of healthy fetuses may result in anemia, hydrops, and death....
13.
Penkert R, Patel N, Webby R, Ross T, Hurwitz J
Vaccines (Basel) . 2021 Jan; 9(2). PMID: 33498232
The improvement of influenza virus vaccines and the development of a universal product have been long-standing goals in pre-clinical and clinical research. To meet these goals and to understand the...
14.
Samarasinghe A, Penkert R, Hurwitz J, Sealy R, LeMessurier K, Hammond C, et al.
Biomedicines . 2020 Oct; 8(10). PMID: 33036262
Asthma affects over 8% of the pediatric population in the United States, and Memphis, Tennessee has been labeled an asthma capital. Plasma samples were analyzed for biomarker profiles from 95...
15.
Penkert R, Smith A, Hrincius E, McCullers J, Vogel P, Smith A, et al.
J Infect Dis . 2020 Sep; 223(10):1806-1816. PMID: 32959872
Background: Secondary bacterial coinfections are ranked as a leading cause of hospitalization and morbid conditions associated with influenza. Because vitamin A deficiency (VAD) and insufficiency are frequent in both developed...
16.
Penkert R, Cortez V, Karlsson E, Livingston B, Surman S, Li Y, et al.
Obesity (Silver Spring) . 2020 Aug; 28(9):1631-1636. PMID: 32779401
Objective: Individuals with obesity suffer from an increased susceptibility to severe respiratory viral infections and respond poorly to vaccinations, making it imperative to identify interventions. Recent evidence suggesting that obesity...
17.
Surman S, Penkert R, Sealy R, Jones B, Marion T, Vogel P, et al.
Int J Mol Sci . 2020 Aug; 21(15). PMID: 32759702
Vitamin A is an important regulator of immune protection, but it is often overlooked in studies of infectious disease. Vitamin A binds an array of nuclear receptors (e.g., retinoic acid...
18.
Jones B, Penkert R, Surman S, Sealy R, Hurwitz J
Int J Mol Sci . 2020 Jul; 21(14). PMID: 32679815
Questions concerning the influences of nuclear receptors and their ligands on mammalian B cells are vast in number. Here, we briefly review the effects of nuclear receptor ligands, including estrogen...
19.
Madan R, Penkert R, Surman S, Jones B, Houston J, Lamour J, et al.
Clin Transplant . 2020 Jun; 34(10):e14021. PMID: 32575155
Introduction: Hypogammaglobulinemia has not been well studied in pediatric solid organ transplant (SOT) recipients. We evaluated plasma immunoglobulin (Ig) and lymphocyte phenotypes among 31 pediatric heart and kidney recipients for...
20.
Penkert R, Hankins J, Young N, Hurwitz J
Viral Immunol . 2020 May; 33(4):342-350. PMID: 32366204
When an individual is exposed to a viral pathogen for the first time, the adaptive immune system is naive and cannot prevent virus replication. The consequence may be severe disease....