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Rex M Tyrrell

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Articles 31
Citations 499
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Recent Articles
11.
Lund A, Hurst T, Tyrrell R, Thompson D
Med Sci Sports Exerc . 2010 Aug; 43(4):578-83. PMID: 20798662
Purpose: Regular exercise is inversely related to markers of chronic inflammation, but we do not know to what extent these changes are the product of recent exercise behavior. The aim...
12.
Wagener F, Scharstuhl A, Tyrrell R, Von den Hoff J, Jozkowicz A, Dulak J, et al.
Curr Drug Targets . 2010 Aug; 11(12):1571-85. PMID: 20704545
Wound healing is an intricate process requiring the concerted action of keratinocytes, fibroblasts, endothelial cells, and macrophages. Here, we review the literature on normal wound healing and the pathological forms...
13.
Thompson D, Markovitch D, Betts J, Mazzatti D, Turner J, Tyrrell R
J Appl Physiol (1985) . 2010 Apr; 108(4):769-79. PMID: 20368384
Regular exercise may improve systemic markers of chronic inflammation, but direct evidence and dose-response information is lacking. The objective of this study was to examine the effect and time course...
14.
Pascu S, Waghorn P, Kennedy B, Arrowsmith R, Bayly S, Dilworth J, et al.
Chem Asian J . 2010 Feb; 5(3):506-19. PMID: 20169605
Copper bis(4-ethyl-3-thiosemicarbazonato) acenaphthenequinone (1) and copper bis(4-methyl-3-thiosemicarbazonato) acenaphthenequinone (2) are synthesized and characterized in solution, in the solid state, and radiolabeled. Serum-protein binding radioassays show good stability in solution and...
15.
Zhong J, Edwards G, Raval C, Li H, Tyrrell R
Photochem Photobiol Sci . 2010 Jan; 9(1):18-24. PMID: 20062840
Ultraviolet-A (UVA, 320-380 nm) radiation is an oxidative stress that strongly induces heme oxygenase 1 (HO-1) expression in cultured human primary skin fibroblasts (FEK4). In this study, we show that...
16.
Zhong J, Raval C, Edwards G, Tyrrell R
Free Radic Biol Med . 2009 Oct; 48(2):196-206. PMID: 19874887
Ultraviolet A (UVA) radiation is an oxidizing agent that strongly induces the heme oxygenase 1 (HO-1) gene and expression of the protein in cultured human skin fibroblasts but weakly induces...
17.
Dixon N, Hurst T, Talbot D, Tyrrell R, Thompson D
J Appl Physiol (1985) . 2009 May; 107(1):63-8. PMID: 19423836
Physical activity modifies some postprandial responses such as glycemic control, although it is unclear whether this translates into lower postprandial inflammation. Our objective in this study was to determine whether...
18.
Markovitch D, Tyrrell R, Tauler P, Frystyk J, Stokes K, Thompson D
Nutrition . 2009 Jan; 25(6):668-75. PMID: 19121922
Objective: We tested the hypothesis that lycopene supplementation reduces the expression of oxidant-responsive heme oxygenase-1 (HO-1) in basal conditions and in response to an oxidant challenge and determined whether this...
19.
Reeve V, Tyrrell R, Allanson M, Domanski D, Blyth L
J Invest Dermatol . 2008 Dec; 129(6):1539-46. PMID: 19110542
The proinflammatory cytokine IL-6 is released in the skin following UVB irradiation, but its potential for photoimmune modulation remains unclear. This study utilizes IL-6-deficient mice to demonstrate that IL-6 does...
20.
Markovitch D, Tyrrell R, Thompson D
J Appl Physiol (1985) . 2008 May; 105(1):260-5. PMID: 18467550
Strenuous exercise induces an initial pro- and subsequent anti-inflammatory response, and it has been suggested that this may be one of the ways that regular exercise reduces chronic inflammation and...