Renu Agarwal
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Explore the profile of Renu Agarwal including associated specialties, affiliations and a list of published articles.
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91
Citations
846
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Recent Articles
11.
Hassan M, Razali N, Bakar A, Abu Hanipah N, Agarwal R
Exp Biol Med (Maywood)
. 2023 Oct;
248(16):1425-1436.
PMID: 37873757
Connective tissue growth factor (CTGF) is a distinct signaling molecule modulating many physiological and pathophysiological processes. This protein is upregulated in numerous fibrotic diseases that involve extracellular matrix (ECM) remodeling....
12.
Sadikan M, Abdul Nasir N, Lambuk L, Mohamud R, Reshidan N, Low E, et al.
BMC Ophthalmol
. 2023 Oct;
23(1):421.
PMID: 37858128
Diabetic retinopathy (DR), one of the leading causes of visual impairment and blindness worldwide, is one of the major microvascular complications in diabetes mellitus (DM). Globally, DR prevalence among DM...
13.
Agarwal R, Agarwal P, Iezhitsa I
Expert Opin Drug Discov
. 2023 Aug;
18(11):1287-1300.
PMID: 37608634
Introduction: Animal models are widely used in glaucoma-related research. Since the elevated intraocular pressure (IOP) is a major risk factor underlying the disease pathogenesis, animal models with high IOP are...
14.
Sadikan M, Abdul Nasir N, Bakar N, Iezhitsa I, Agarwal R
BMC Complement Med Ther
. 2023 Jun;
23(1):179.
PMID: 37268913
Background: Diabetic retinopathy (DR) is the second commonest microvascular complication of diabetes mellitus. It is characterized by chronic inflammation and angiogenesis. Palm oil-derived tocotrienol-rich fraction (TRF), a substance with anti-inflammatory...
15.
Abd Ghapor A, Abdul Nasir N, Iezhitsa I, Agarwal R, Razali N
Neurosci Res
. 2023 Feb;
193:1-12.
PMID: 36796452
Adenosine A1 receptors (AA1R) have been shown to counteract N-methyl-D-aspartate (NMDA)-mediated glutamatergic excitotoxicity. In the present study, we investigated the role of AA1R in neuroprotection by trans-resveratrol (TR) against NMDA-induced...
16.
Abdul Ghani N, Abdul Nasir N, Lambuk L, Sadikan M, Agarwal R, Ramli N
Graefes Arch Clin Exp Ophthalmol
. 2023 Jan;
261(6):1587-1596.
PMID: 36622408
Purpose: Angiogenesis in diabetic retinopathy (DR) is associated with increased retinal expression of angiopoietin-2 (Ang-2) and protein kinase C (PKC). Tocotrienol-rich fraction (TRF) has been shown to reduce the expression...
17.
Sadikan M, Abdul Nasir N, Iezhitsa I, Agarwal R
Biomed Pharmacother
. 2022 Sep;
153:113533.
PMID: 36076612
Oxidative stress, a key player in diabetic retinopathy (DR), is associated with retinal cell apoptosis. This study investigated the effect of tocotrienol-rich fraction (TRF), a potent antioxidant, towards visual behaviour,...
18.
Jasmiad N, Abd Ghani R, Agarwal R, Ismail Z, Mohd Abdullah A, Idorus M
BMC Ophthalmol
. 2022 Sep;
22(1):357.
PMID: 36057550
Background: Diabetic retinopathy (DR) is a serious complication of longstanding type 2 diabetes mellitus (T2DM), a leading cause of blindness and visual disability in the world. The aim of this...
19.
Lazaldin M, Iezhitsa I, Agarwal R, Agarwal P, Ismail N
Neural Regen Res
. 2022 Jul;
18(2):382-388.
PMID: 35900434
Amyloid-beta (Aβ)-related alterations, similar to those found in the brains of patients with Alzheimer's disease, have been observed in the retina of patients with glaucoma. Decreased levels of brain-derived neurotrophic...
20.
Abd Aziz N, Iezhitsa I, Agarwal R, Bakar N, Abd Latiff A, Ismail N
J Neuropathol Exp Neurol
. 2022 Jul;
81(8):596-613.
PMID: 35799401
Given the neuroprotective effects of trans-resveratrol (RV), this study aimed to investigate the involvement of the adenosine A1 receptor (A1R) in RV-mediated neuroprotection in a rat intracerebral hemorrhage (ICH) model...