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Puneet Agarwal

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Articles 92
Citations 1585
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Recent Articles
1.
Arumugam P, Singh L, Agarwal P, Shetti S, Sharan S
Cureus . 2024 Aug; 16(7):e64758. PMID: 39156324
Progressive multifocal leukoencephalopathy (PML) is considered an often fatal, demon-leading disease primarily associated with immunosuppression. Immunocompromised individuals predominantly exhibit this manifestation, while immunocompatible patients rarely encounter it. We present a...
2.
Iezhitsa I, Agarwal R, Agarwal P
Vision Res . 2024 May; 221:108434. PMID: 38805893
Treatment of glaucoma, the leading cause of irreversible blindness, remains challenging. The apoptotic loss of retinal ganglion cells (RGCs) in glaucoma is the pathological hallmark. Current treatments often remain suboptimal...
3.
Dawson A, Zarou M, Prasad B, Bittencourt-Silvestre J, Zerbst D, Himonas E, et al.
Nat Commun . 2024 Feb; 15(1):1090. PMID: 38316788
Macrophages are fundamental cells of the innate immune system that support normal haematopoiesis and play roles in both anti-cancer immunity and tumour progression. Here we use a chimeric mouse model...
4.
Agarwal R, Agarwal P, Iezhitsa I
Expert Opin Drug Discov . 2023 Aug; 18(11):1287-1300. PMID: 37608634
Introduction: Animal models are widely used in glaucoma-related research. Since the elevated intraocular pressure (IOP) is a major risk factor underlying the disease pathogenesis, animal models with high IOP are...
5.
Jose E, Agarwal P, Zhuang J
Nat Hazards (Dordr) . 2023 Jun; :1-27. PMID: 37360797
In the current century, wildfires have shown an increasing trend, causing a huge amount of direct and indirect losses in society. Different methods and efforts have been employed to reduce...
6.
Bennett J, Ishikawa C, Agarwal P, Yeung J, Sampson A, Uible E, et al.
Blood . 2023 May; 142(11):989-1007. PMID: 37172199
Dysregulation of innate immune signaling is a hallmark of hematologic malignancies. Recent therapeutic efforts to subvert aberrant innate immune signaling in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) have...
7.
Muto T, Walker C, Agarwal P, Vick E, Sampson A, Choi K, et al.
Haematologica . 2023 Apr; 108(10):2715-2729. PMID: 37102608
Inflammation is associated with the pathogenesis of myelodysplastic syndromes (MDS) and emerging evidence suggests that MDS hematopoietic stem and progenitor cells (HSPC) exhibit an altered response to inflammation. Deletion of...
8.
Anderson N, Sheth V, Li H, Harris M, Qiu S, Crossman D, et al.
Leukemia . 2022 Dec; 37(3):560-570. PMID: 36550214
Fms-like tyrosine kinase 3 (Flt3) tyrosine kinase inhibitors (Flt3-TKI) have improved outcomes for patients with Flt3-mutated acute myeloid leukemia (AML) but are limited by resistance and relapse, indicating persistence of...
9.
Bhosale K, Nath R, Pandit N, Agarwal P, Khairnar S, Yadav B, et al.
Int J Heart Fail . 2022 Oct; 2(2):131-144. PMID: 36263288
Background And Objectives: Identifying the patients with acute heart failure (HF) at high risk for rehospitalization after hospital discharge will enable proper optimization of treatment. This study is aimed to...
10.
Lazaldin M, Iezhitsa I, Agarwal R, Agarwal P, Ismail N
Neural Regen Res . 2022 Jul; 18(2):382-388. PMID: 35900434
Amyloid-beta (Aβ)-related alterations, similar to those found in the brains of patients with Alzheimer's disease, have been observed in the retina of patients with glaucoma. Decreased levels of brain-derived neurotrophic...