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Renske Keeman

Explore the profile of Renske Keeman including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 2971
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Recent Articles
1.
Hoppe R, Winter S, Lo W, Michailidou K, Bolla M, Keeman R, et al.
NPJ Breast Cancer . 2025 Feb; 11(1):18. PMID: 39971965
The role of germline genetics in adjuvant aromatase inhibitor (AI) treatment efficacy in ER-positive breast cancer is poorly understood. We employed a two-stage candidate gene approach to examine associations between...
2.
Hurson A, Ahearn T, Koka H, Jenkins B, Harris A, Roberts S, et al.
medRxiv . 2024 Aug; PMID: 39108508
Background: Breast cancer is comprised of distinct molecular subtypes. Studies have reported differences in risk factor associations with breast cancer subtypes, especially by tumor estrogen receptor (ER) status, but their...
3.
Hurson A, Ahearn T, Koka H, Jenkins B, Harris A, Roberts S, et al.
J Natl Cancer Inst . 2024 Jul; 116(12):1992-2002. PMID: 39018167
Background: Breast cancer consists of distinct molecular subtypes. Studies have reported differences in risk factor associations with breast cancer subtypes, especially by tumor estrogen receptor (ER) status, but their consistency...
4.
Wilcox N, Dumont M, Gonzalez-Neira A, Carvalho S, Joly Beauparlant C, Crotti M, et al.
Nat Genet . 2023 Sep; 55(11):2009. PMID: 37752376
No abstract available.
5.
Wilcox N, Dumont M, Gonzalez-Neira A, Carvalho S, Joly Beauparlant C, Crotti M, et al.
Nat Genet . 2023 Aug; 55(9):1435-1439. PMID: 37592023
Linkage and candidate gene studies have identified several breast cancer susceptibility genes, but the overall contribution of coding variation to breast cancer is unclear. To evaluate the role of rare...
6.
Middha P, Wang X, Behrens S, Bolla M, Wang Q, Dennis J, et al.
Breast Cancer Res . 2023 Aug; 25(1):93. PMID: 37559094
Background: Genome-wide studies of gene-environment interactions (G×E) may identify variants associated with disease risk in conjunction with lifestyle/environmental exposures. We conducted a genome-wide G×E analysis of ~ 7.6 million common...
7.
Muranen T, Morra A, Khan S, Barnes D, Bolla M, Dennis J, et al.
NPJ Breast Cancer . 2023 May; 9(1):37. PMID: 37173335
We assessed the PREDICT v 2.2 for prognosis of breast cancer patients with pathogenic germline BRCA1 and BRCA2 variants, using follow-up data from 5453 BRCA1/2 carriers from the Consortium of...
8.
Morra A, Mavaddat N, Muranen T, Ahearn T, Allen J, Andrulis I, et al.
Am J Hum Genet . 2023 Feb; 110(3):475-486. PMID: 36827971
Evidence linking coding germline variants in breast cancer (BC)-susceptibility genes other than BRCA1, BRCA2, and CHEK2 with contralateral breast cancer (CBC) risk and breast cancer-specific survival (BCSS) is scarce. The...
9.
Lopes Cardozo J, Andrulis I, Bojesen S, Dork T, Eccles D, Fasching P, et al.
J Clin Oncol . 2023 Jan; 41(10):1849-1863. PMID: 36689693
Purpose: A polygenic risk score (PRS) consisting of 313 common genetic variants (PRS) is associated with risk of breast cancer and contralateral breast cancer. This study aimed to evaluate the...
10.
Giardiello D, Hooning M, Hauptmann M, Keeman R, Heemskerk-Gerritsen B, Becher H, et al.
Breast Cancer Res . 2022 Nov; 24(1):82. PMID: 36419099
No abstract available.