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Rene Lerch

Explore the profile of Rene Lerch including associated specialties, affiliations and a list of published articles. Areas
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Articles 67
Citations 752
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Recent Articles
1.
Muller H, Reverdin S, Burri H, Shah D, Lerch R
Echocardiography . 2013 Oct; 31(4):499-507. PMID: 24128369
Aims: Real time full-volume 3D echocardiography (3DE) allows rapid and noninvasive measurement of left (LA) and right atrial (RA) volume without geometric assumptions. Different algorithms from different commercial providers are...
2.
Garin N, Carballo S, Gerstel E, Lerch R, Meyer P, Zare M, et al.
Eur J Intern Med . 2012 Nov; 23(8):760-4. PMID: 23122393
Background: Evidence-based therapies can lower the risk of death or hospital admission in heart failure (HF) patients, but are underprescribed. Critical pathways are one means of supporting systematic use of...
3.
Montessuit C, Lerch R
Biochim Biophys Acta . 2012 Sep; 1833(4):848-56. PMID: 22967513
The ability of the heart muscle to derive energy from a wide variety of substrates provides the myocardium with remarkable capacity to adapt to the ever-changing metabolic environment depending on...
4.
Montecucco F, Bauer I, Braunersreuther V, Bruzzone S, Akhmedov A, Luscher T, et al.
Antioxid Redox Signal . 2012 Mar; 18(6):630-41. PMID: 22452634
Aims: Nicotinamide phosphoribosyltransferase (Nampt) is a key enzyme for nicotinamide adenine dinucleotide (NAD(+)) biosynthesis, and recent evidence indicates its role in inflammatory processes. Here, we investigated the potential effects of...
5.
Pellieux C, Montessuit C, Papageorgiou I, Pedrazzini T, Lerch R
Am J Physiol Heart Circ Physiol . 2012 Mar; 302(9):H1795-805. PMID: 22408021
Normal myocardium adapts to increase of nutritional fatty acid supply by upregulation of regulatory proteins of the fatty acid oxidation pathway. Because advanced heart failure is associated with reduction of...
6.
Asrih M, Lerch R, Papageorgiou I, Pellieux C, Montessuit C
Am J Physiol Endocrinol Metab . 2012 Feb; 302(7):E872-84. PMID: 22297301
Stimulation of glucose transport in response to insulin or metabolic stress is an important determinant of cardiac myocyte function and survival, particularly during ischemia-reperfusion episodes. The impact of dyslipidemia and...
7.
Delattre B, Van De Ville D, Braunersreuther V, Pellieux C, Hyacinthe J, Lerch R, et al.
IEEE Trans Biomed Eng . 2011 Nov; 59(4):929-35. PMID: 22057042
Accurate assessment of mice cardiac function with magnetic resonance imaging is essential for longitudinal studies and for drug development related to cardiovascular diseases. Whereas dedicated small animal MR scanners are...
8.
Asrih M, Pellieux C, Papageorgiou I, Lerch R, Montessuit C
Am J Physiol Endocrinol Metab . 2011 Jul; 301(5):E836-43. PMID: 21771966
We previously demonstrated that microtubule disruption impairs stimulation of glucose uptake in cardiomyocytes and that 9-cis retinoic acid (9cRA) treatment preserved both microtubule integrity and stimulated glucose transport. Herein we...
9.
Muller H, Park C, Lerch R
Arch Cardiovasc Dis . 2011 Mar; 104(2):140-1. PMID: 21402351
No abstract available.
10.
Shende P, Plaisance I, Morandi C, Pellieux C, Berthonneche C, Zorzato F, et al.
Circulation . 2011 Mar; 123(10):1073-82. PMID: 21357822
Background: Cardiac hypertrophy involves growth responses to a variety of stimuli triggered by increased workload. It is an independent risk factor for heart failure and sudden death. Mammalian target of...