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Rene L Vidal

Explore the profile of Rene L Vidal including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 1004
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Recent Articles
11.
Sepulveda D, Grunenwald F, Vidal A, Troncoso-Escudero P, Cisternas-Olmedo M, Villagra R, et al.
Sci Rep . 2022 Feb; 12(1):2038. PMID: 35132125
Insulin-like growth factor 2 (IGF2) and autophagy-related genes have been proposed as biomolecules of interest related to idiopathic Parkinson's disease (PD). The objective of this study was to determine the...
12.
Perez-Arancibia R, Ordonez J, Rivas A, Pihan P, Sagredo A, Ahumada U, et al.
PLoS One . 2021 Jul; 16(7):e0254834. PMID: 34324551
Accumulation of misfolded proteins in the brain is a common hallmark of most age-related neurodegenerative diseases. Previous studies from our group identified the presence of anti-inflammatory and antioxidant compounds in...
13.
Urra H, Henriquez D, Canovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, et al.
Nat Cell Biol . 2021 Apr; 23(5):577. PMID: 33907311
No abstract available.
14.
Vidal R, Sepulveda D, Troncoso-Escudero P, Garcia-Huerta P, Gonzalez C, Plate L, et al.
Mol Ther . 2021 Feb; 29(5):1862-1882. PMID: 33545358
Alteration to endoplasmic reticulum (ER) proteostasis is observed in a variety of neurodegenerative diseases associated with abnormal protein aggregation. Activation of the unfolded protein response (UPR) enables an adaptive reaction...
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Troncoso-Escudero P, Sepulveda D, Perez-Arancibia R, Parra A, Arcos J, Grunenwald F, et al.
Front Aging Neurosci . 2020 Oct; 12:571185. PMID: 33101007
Movement disorders are neurological conditions in which patients manifest a diverse range of movement impairments. Distinct structures within the basal ganglia of the brain, an area involved in movement regulation,...
17.
Garcia-Huerta P, Troncoso-Escudero P, Wu D, Thiruvalluvan A, Cisternas-Olmedo M, Henriquez D, et al.
Acta Neuropathol . 2020 Jul; 140(5):737-764. PMID: 32642868
Impaired neuronal proteostasis is a salient feature of many neurodegenerative diseases, highlighting alterations in the function of the endoplasmic reticulum (ER). We previously reported that targeting the transcription factor XBP1,...
18.
Troncoso-Escudero P, Parra A, Nassif M, Vidal R
Front Neurol . 2018 Nov; 9:860. PMID: 30459700
Neuroinflammation is one of the most important processes involved in the pathogenesis of Parkinson's disease (PD). The current concept of neuroinflammation comprises an inflammation process, which occurs in the central...
19.
Urra H, Henriquez D, Canovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, et al.
Nat Cell Biol . 2018 Aug; 20(10):1228. PMID: 30089843
In the version of this Article originally published, the competing interests statement was missing. The authors declare no competing interests; this statement has now been added in all online versions...
20.
Urra H, Henriquez D, Canovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, et al.
Nat Cell Biol . 2018 Jul; 20(8):942-953. PMID: 30013108
Maintenance of endoplasmic reticulum (ER) proteostasis is controlled by a signalling network known as the unfolded protein response (UPR). Here, we identified filamin A as a major binding partner of...