Renata M C Brandt
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Explore the profile of Renata M C Brandt including associated specialties, affiliations and a list of published articles.
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25
Citations
1149
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Recent Articles
1.
Vermeij W, Alyodawi K, van Galen I, von der Heide J, Birkisdottir M, Vant Sant L, et al.
J Cachexia Sarcopenia Muscle
. 2024 Sep;
15(6):2361-2374.
PMID: 39245994
Background: Ageing is a complex multifactorial process, impacting all organs and tissues, with DNA damage accumulation serving as a common underlying cause. To decelerate ageing, various strategies have been applied...
2.
Reuvers T, Grandia V, Brandt R, Arab M, Maas S, Bos E, et al.
Cancers (Basel)
. 2024 Jul;
16(14).
PMID: 39061156
Peptide receptor radionuclide therapy (PRRT) using Lu-DOTA-TATE has recently been evaluated for the treatment of meningioma patients. However, current knowledge of the underlying radiation biology is limited, in part due...
3.
He Y, Yang W, Huang L, Mever M, Ramautar R, Harms A, et al.
J Cachexia Sarcopenia Muscle
. 2024 May;
15(3):868-882.
PMID: 38689513
Background: Sarcopenia is characterized by loss of skeletal muscle mass and function, and is a major risk factor for disability and independence in the elderly. Effective medication is not available....
4.
van der Linden J, Stefens S, Heredia-Genestar J, Ridwan Y, Brandt R, van Vliet N, et al.
Aging Cell
. 2024 Mar;
23(5):e14126.
PMID: 38451018
Cardiovascular diseases are the number one cause of death globally. The most important determinant of cardiovascular health is a person's age. Aging results in structural changes and functional decline of...
5.
Birkisdottir M, Vant Sant L, Brandt R, Barnhoorn S, Hoeijmakers J, Vermeij W, et al.
Front Aging Neurosci
. 2023 Feb;
14:1095801.
PMID: 36760711
Dietary restriction (DR) is a universal anti-aging intervention, which reduces age-related nervous system pathologies and neurological decline. The degree to which the neuroprotective effect of DR operates by attenuating cell...
6.
de Boer M, Te Lintel Hekkert M, Chang J, van Thiel B, Martens L, Bos M, et al.
Aging Cell
. 2023 Feb;
22(3):e13768.
PMID: 36756698
Heart failure has reached epidemic proportions in a progressively ageing population. The molecular mechanisms underlying heart failure remain elusive, but evidence indicates that DNA damage is enhanced in failing hearts....
7.
Gyenis A, Chang J, Demmers J, Bruens S, Barnhoorn S, Brandt R, et al.
Nat Genet
. 2023 Jan;
55(2):268-279.
PMID: 36658433
Gene expression profiling has identified numerous processes altered in aging, but how these changes arise is largely unknown. Here we combined nascent RNA sequencing and RNA polymerase II chromatin immunoprecipitation...
8.
Birkisdottir M, van Galen I, Brandt R, Barnhoorn S, van Vliet N, van Dijk C, et al.
Front Aging
. 2022 Dec;
3:1086552.
PMID: 36506463
[This corrects the article DOI: 10.3389/fragi.2022.1005322.].
9.
Birkisdottir M, van Galen I, Brandt R, Barnhoorn S, van Vliet N, van Dijk C, et al.
Front Aging
. 2022 Oct;
3:1005322.
PMID: 36313181
Despite efficient repair, DNA damage inevitably accumulates with time affecting proper cell function and viability, thereby driving systemic aging. Interventions that either prevent DNA damage or enhance DNA repair are...
10.
Ataei Ataabadi E, Golshiri K, Juttner A, de Vries R, Van den Berg-Garrelds I, Nagtzaam N, et al.
Aging Cell
. 2022 Aug;
21(9):e13683.
PMID: 36029161
DNA damage is a causative factor in ageing of the vasculature and other organs. One of the most important vascular ageing features is reduced nitric oxide (NO)soluble guanylate cyclase (sGC)-cyclic...