Rena Onoguchi-Mizutani
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Explore the profile of Rena Onoguchi-Mizutani including associated specialties, affiliations and a list of published articles.
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11
Citations
103
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Recent Articles
1.
Taniue K, Sugawara A, Zeng C, Han H, Gao X, Shimoura Y, et al.
Nat Commun
. 2024 Oct;
15(1):8684.
PMID: 39419981
RNA surveillance systems degrade aberrant RNAs that result from defective transcriptional termination, splicing, and polyadenylation. Defective RNAs in the nucleus are recognized by RNA-binding proteins and MTR4, and are degraded...
2.
Noguchi K, Suzuki H, Abe R, Horiuchi K, Onoguchi-Mizutani R, Akimitsu N, et al.
Cell Rep
. 2024 Sep;
43(9):114734.
PMID: 39283744
Membrane-less subcellular compartments play important roles in various cellular functions. Although techniques exist to identify components of cellular bodies, a comprehensive method for analyzing both static and dynamic states has...
3.
Onoguchi-Mizutani R, Akimitsu N
J Biochem
. 2022 Jan;
171(3):269-276.
PMID: 35080597
Stress response is important for sensing and adapting to environmental changes. Recently, RNA-protein (RNP) condensates, which are a type of membrane-less organelle formed by liquid-liquid phase separation, have been proposed...
4.
Tanu T, Taniue K, Imamura K, Onoguchi-Mizutani R, Han H, Jensen T, et al.
RNA Biol
. 2021 Sep;
18(sup1):537-547.
PMID: 34470577
Many long noncoding RNAs (lncRNAs) are localized in the nucleus and play important roles in various biological processes, including cell proliferation, differentiation and antiviral response. Yet, it remains unclear how...
5.
Yamamoto K, Goyama S, Asada S, Fujino T, Yonezawa T, Sato N, et al.
Cell Rep
. 2021 Aug;
36(8):109576.
PMID: 34433054
Paraspeckles are membraneless organelles formed through liquid-liquid phase separation and consist of multiple proteins and RNAs, including NONO, SFPQ, and NEAT1. The role of paraspeckles and the component NONO in...
6.
Onoguchi-Mizutani R, Kirikae Y, Ogura Y, Gutschner T, Diederichs S, Akimitsu N
J Cell Sci
. 2021 May;
134(10).
PMID: 34028540
The heat-shock response is critical for the survival of all organisms. Metastasis-associated long adenocarcinoma transcript 1 (MALAT1) is a long noncoding RNA localized in nuclear speckles, but its physiological role...
7.
Shirahama S, Onoguchi-Mizutani R, Kawata K, Taniue K, Miki A, Kato A, et al.
Sci Rep
. 2020 Nov;
10(1):19406.
PMID: 33173149
Long non-coding RNAs (lncRNAs) play vital roles in the pathogenesis of infectious diseases, but the role of lncRNAs in herpes simplex virus 1 (HSV-1) infection remains unknown. Using RNA sequencing...
8.
Onoguchi-Mizutani R, Kishi Y, Ogura Y, Nishimura Y, Imamachi N, Suzuki Y, et al.
J Biochem
. 2020 Nov;
169(4):497-505.
PMID: 33170212
The heat-shock response is a crucial system for survival of organisms under heat stress. During heat-shock stress, gene expression is globally suppressed, but expression of some genes, such as chaperone...
9.
Imamura K, Takaya A, Ishida Y, Fukuoka Y, Taya T, Nakaki R, et al.
EMBO J
. 2018 Jun;
37(13).
PMID: 29880601
Cytoplasmic mRNA degradation controls gene expression to help eliminate pathogens during infection. However, it has remained unclear whether such regulation also extends to nuclear RNA decay. Here, we show that...
10.
Tano K, Onoguchi-Mizutani R, Yeasmin F, Uchiumi F, Suzuki Y, Yada T, et al.
Front Genet
. 2018 Apr;
8:208.
PMID: 29632545
The MALAT1 long noncoding RNA is strongly linked to cancer progression. Here we report a MALAT1 function in repressing the promoter of tumor suppressor gene. and , well-known p53 targets,...