Reinhold Schirmbeck
Overview
Explore the profile of Reinhold Schirmbeck including associated specialties, affiliations and a list of published articles.
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Articles
88
Citations
1616
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Recent Articles
1.
Lahusen A, Cai J, Schirmbeck R, Wellstein A, Kleger A, Seufferlein T, et al.
Sci Rep
. 2024 Apr;
14(1):9377.
PMID: 38654067
Poor treatment responses of pancreatic ductal adenocarcinoma (PDAC) are in large part due to tumor heterogeneity and an immunosuppressive desmoplastic tumor stroma that impacts interactions with cells in the tumor...
2.
Pflumm D, Seidel A, Klein F, Gross R, Krutzke L, Kochanek S, et al.
Front Immunol
. 2023 Sep;
14:1231274.
PMID: 37753087
A multitude of alterations in the old immune system impair its functional integrity. Closely related, older individuals show, for example, a reduced responsiveness to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)...
3.
Qiu N, Srikanth A, Mulaw M, Tharehalli U, Selvachandran S, Wagner M, et al.
Oncoimmunology
. 2023 Jun;
12(1):2215096.
PMID: 37261086
The expression of viral antigens in chronic hepatitis B virus (HBV) infection drives continuous liver inflammation, one of the main risk factors to develop liver cancer. HBV developed immune-suppressive functions...
4.
Roman-Sosa G, Leske A, Ficht X, Dau T, Holzerland J, Hoenen T, et al.
Vaccines (Basel)
. 2022 Feb;
10(2).
PMID: 35214632
New World arenaviruses are rodent-transmitted viruses and include a number of pathogens that are responsible for causing severe human disease. This includes Junín virus (JUNV), which is the causative agent...
5.
Stifter K, Krieger J, Ruths L, Gout J, Mulaw M, Lechel A, et al.
J Immunother Cancer
. 2020 Sep;
8(2).
PMID: 32868392
Background: Many cancer cells express a major histocompatibility complex class I low/ programmed cell death 1 ligand 1 positive (MHC-I/PD-L1) cell surface profile. For immunotherapy, there is, thus, an urgent...
6.
Stifter K, Dekhtiarenko I, Krieger J, Tissot A, Seufferlein T, Wagner M, et al.
Vaccine
. 2020 Apr;
38(21):3711-3719.
PMID: 32278524
Somatic mutations in tumors often generate neoproteins that contain MHC-I-binding neoepitopes. Little is known if and how efficient tumor-specific neoantigens activate CD8 T cells. Here, we asked whether a de...
7.
Spyrantis A, Krieger J, Stifter K, Boehm B, Schirmbeck R
Cell Mol Immunol
. 2019 Oct;
17(6):659-661.
PMID: 31649307
No abstract available.
8.
Svinarenko M, Katz S, Tharehalli U, Mulaw M, Maier H, Sunami Y, et al.
Cancers (Basel)
. 2019 Sep;
11(10).
PMID: 31546614
Background: Most liver tumors arise on the basis of chronic liver diseases that trigger inflammatory responses. Besides inflammation, subsequent defects in the p53-signaling pathway frequently occurs in liver cancer. In...
9.
Krieger J, Riedl P, Stifter K, Roman-Sosa G, Seufferlein T, Wagner M, et al.
Mol Ther
. 2019 Feb;
27(3):661-672.
PMID: 30713086
Hepatitis B virus (HBV) core (HBV-C) antigens with homologous or heterologous HIV-tat48-57-like (HBV-C149tat) cationic domains non-specifically bind cellular RNA in vector-transfected cells. Here, we investigated whether RNA-binding to cationic domains...
10.
Stifter K, Schuster C, Krieger J, Spyrantis A, Boehm B, Schirmbeck R
Mol Ther Methods Clin Dev
. 2019 Jan;
12:123-133.
PMID: 30623001
DNA vaccines against autoimmune type 1 diabetes (T1D) contain a nonpredictable risk to induce autoreactive T cell responses rather than a protective immunity. Little is known if (and how) antigen...