Reinhild Klein
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Explore the profile of Reinhild Klein including associated specialties, affiliations and a list of published articles.
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89
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1521
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Recent Articles
1.
Schad F, Thronicke A, Hofheinz R, Klein R, Grabowski P, Oei S, et al.
Pharmaceuticals (Basel)
. 2025 Jan;
17(12.
PMID: 39770555
Recent advancements in cancer treatment have shown the potential of immune checkpoint blockade (ICB) plus L. therapy in improving survival rates for patients with advanced or metastatic non-small-cell lung cancer...
2.
Martac I, Beer S, Schenk A, Ahmad O, Maier C, Demirel G, et al.
Front Immunol
. 2025 Jan;
15:1510942.
PMID: 39744626
Introduction: Multiple myeloma (MM) is an uncontrolled plasma cell proliferation in the bone marrow, leading to immune dysregulation with impaired humoral immune responses. Conversely, cellular-based responses play a vital role...
3.
Wagner R, Buettner J, Heni M, Fritsche L, Kullmann S, Wagmuller M, et al.
BMC Med
. 2024 Nov;
22(1):558.
PMID: 39593091
Background: The potential impact of specific food additives, common in Western diets, on the risk of developing type 2 diabetes is not well understood. This study focuses on carrageenan, a...
4.
Kocijancic M, Goj T, Peter A, Klein R, Horber S
J Clin Med
. 2024 Aug;
13(15).
PMID: 39124794
Antiphospholipid antibody (aPL) testing is critical for the classification of antiphospholipid syndrome. The 2023 ACR/EULAR classification criteria recommend the use of enzyme-linked immunosorbent assays (ELISAs) and specific thresholds for aPL...
5.
6.
Kramer K, Pecher A, Henes J, Klein R
Clin Exp Rheumatol
. 2024 Mar;
42(8):1571-1580.
PMID: 38530662
Objectives: Antinuclear antibodies (ANA) of the IgE-type have been described in several connective tissue disorders (CTD) but not yet in systemic sclerosis (SSc). Aim of the study was, therefore, to...
7.
Pecher A, Klein R, Koetter I, Wagner M, Vogel W, Wirths S, et al.
Arthritis Res Ther
. 2024 Mar;
26(1):75.
PMID: 38509633
Background: Treatment with high-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (aHSCT) is an intensive treatment option for patients with severe forms of systemic sclerosis (SSc). Even though associated...
8.
Hoenisch Gravel N, Nelde A, Bauer J, Muhlenbruch L, Schroeder S, Neidert M, et al.
Nat Commun
. 2023 Nov;
14(1):7472.
PMID: 37978195
T cell recognition of human leukocyte antigen (HLA)-presented tumor-associated peptides is central for cancer immune surveillance. Mass spectrometry (MS)-based immunopeptidomics represents the only unbiased method for the direct identification and...
9.
Autoantibodies to beta tubulin in autoimmune liver diseases-Relation to pANCA and clinical relevance
Preuss B, Frank A, Terjung B, Spengler U, Berg C, Klein R
Clin Exp Immunol
. 2023 Oct;
216(2):146-158.
PMID: 37823420
There was evidence that perinuclear antineutrophil cytoplasmic antibodies (pANCA) in autoimmune liver diseases react with human beta-tubulin-5 (TBB5). Here, we reevaluate the specificity and clinical relevance of anti-TBB5 antibodies. Patients...
10.
Gouttefangeas C, Klein R, Maia A
Front Immunol
. 2023 Jul;
14:1212546.
PMID: 37409132
T cells are main actors of the immune system with an essential role in protection against pathogens and cancer. The molecular key event involved in this absolutely central task is...