Reinhard Schliebs
Overview
Explore the profile of Reinhard Schliebs including associated specialties, affiliations and a list of published articles.
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60
Citations
1638
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Recent Articles
1.
Ortuno-Sahagun D, Schliebs R, Pallas M
Front Cell Neurosci
. 2019 May;
13:118.
PMID: 31105525
No abstract available.
2.
Muche A, Arendt T, Schliebs R
PLoS One
. 2017 Jun;
12(6):e0178127.
PMID: 28617802
Background: Oxidative stress is thought to be a key player in the pathogenesis of neurodegenerative dementia, including Alzheimer's disease (AD). It has been assumed that oxidative stress contributes to the...
3.
Bielarczyk H, Jankowska-Kulawy A, Hofling C, Ronowska A, Gul-Hinc S, Rossner S, et al.
J Alzheimers Dis
. 2015 Sep;
48(4):1083-94.
PMID: 26402099
The pyruvate-derived acetyl-CoA is a principal direct precursor substrate for bulk energy synthesis in the brain. Deficits of pyruvate dehydrogenase in the neocortex are common features of Alzheimer's disease and...
4.
Muche A, Bigl M, Arendt T, Schliebs R
Int J Dev Neurosci
. 2015 Mar;
43:25-34.
PMID: 25797338
Vascular endothelial growth factor (VEGF) has been characterized as a heparin binding angiogenic growth factor displaying high specificity for endothelial cells. It is profoundly accumulated and co-localized with amyloid beta...
5.
Muche A, Burger S, Arendt T, Schliebs R
Nutr Neurosci
. 2013 Nov;
18(1):1-11.
PMID: 24257464
This study stresses the hypothesis whether hypoxic events contribute to formation and deposition of β-amyloid (Aβ) in cerebral blood vessels by affecting the processing of endothelial amyloid precursor protein (APP)....
6.
Hafner A, Glavan G, Obermajer N, Zivin M, Schliebs R, Kos J
Aging Cell
. 2013 Apr;
12(4):604-14.
PMID: 23621429
γ-Enolase is a neurotrophic-like factor promoting growth, differentiation, survival and regeneration of neurons. Its neurotrophic activity is regulated by cysteine protease cathepsin X which cleaves the C-terminal end of the...
7.
Kuznetsova E, Schliebs R
Curr Pharm Des
. 2013 Mar;
19(38):6749-65.
PMID: 23530514
The majority of patients suffering from Alzheimer's disease (AD) demonstrate cerebral vascular changes and impaired regulation of cerebral blood flow, which has been assumed to play an important role in...
8.
Cholinergic denervation exacerbates amyloid pathology and induces hippocampal atrophy in Tg2576 mice
Gil-Bea F, Gerenu G, Aisa B, Kirazov L, Schliebs R, Ramirez M
Neurobiol Dis
. 2012 Jul;
48(3):439-46.
PMID: 22759926
The main pathological hallmarks of Alzheimer's disease (AD) consist of amyloid plaques and neurofibrillary tangles. Hippocampal cell loss, atrophy and cholinergic dysfunction are also features of AD. The present work...
9.
Zarazua S, Burger S, Delgado J, Jimenez-Capdeville M, Schliebs R
Int J Dev Neurosci
. 2011 Mar;
29(4):389-96.
PMID: 21440049
Arsenic poisoning due to contaminated water and soil, mining waste, glass manufacture, select agrochemicals, as well as sea food, affects millions of people world wide. Recently, an involvement of arsenic...
10.
Hartlage-Rubsamen M, Morawski M, Waniek A, Jager C, Zeitschel U, Koch B, et al.
Acta Neuropathol
. 2011 Feb;
121(6):705-19.
PMID: 21301857
In the hippocampal formation of Alzheimer's disease (AD) patients, both focal and diffuse deposits of Aβ peptides appear in a subregion- and layer-specific manner. Recently, pyroglutamate (pGlu or pE)-modified Aβ...