Reina E Itoh
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Explore the profile of Reina E Itoh including associated specialties, affiliations and a list of published articles.
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10
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1011
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Recent Articles
1.
Hikita T, Uehara R, Itoh R, Mitani F, Miyata M, Yoshida T, et al.
Cancer Sci
. 2022 Feb;
113(4):1264-1276.
PMID: 35108425
Cancer cells secrete large amounts of extracellular vesicles (EVs) originating from multivesicular bodies (MVBs). Mature MVBs fuse either with the plasma membrane for release as EVs, often referred as to...
2.
Aoki K, Kondo Y, Naoki H, Hiratsuka T, Itoh R, Matsuda M
Dev Cell
. 2017 Nov;
43(3):305-317.e5.
PMID: 29112851
The biophysical framework of collective cell migration has been extensively investigated in recent years; however, it remains elusive how chemical inputs from neighboring cells are integrated to coordinate the collective...
3.
Takayama Y, Itoh R, Tsuyama T, Uemura T
Genes Cells
. 2014 Apr;
19(6):464-77.
PMID: 24702731
Recessive mutations in the amyotrophic lateral sclerosis 2 (ALS2) gene have been linked to juvenile-onset ALS2. Although one of the molecular functions of the ALS2 protein is clearly the activation...
4.
Itoh R, Kiyokawa E, Aoki K, Nishioka T, Akiyama T, Matsuda M
J Cell Sci
. 2008 Jul;
121(Pt 16):2635-42.
PMID: 18653540
Rac1 has a crucial role in epidermal growth factor (EGF)-induced membrane ruffling, lamellipodial protrusion, and cell migration. Several guanine nucleotide exchange factors (GEFs) including Sos1, Sos2, Tiam1 and Vav2 have...
5.
Yamana N, Arakawa Y, Nishino T, Kurokawa K, Tanji M, Itoh R, et al.
Mol Cell Biol
. 2006 Sep;
26(18):6844-58.
PMID: 16943426
Directed cell migration requires cell polarization and adhesion turnover, in which the actin cytoskeleton and microtubules work critically. The Rho GTPases induce specific types of actin cytoskeleton and regulate microtubule...
6.
Fujioka A, Terai K, Itoh R, Aoki K, Nakamura T, Kuroda S, et al.
J Biol Chem
. 2006 Jan;
281(13):8917-26.
PMID: 16418172
To comprehend the Ras/ERK MAPK cascade, which comprises Ras, Raf, MEK, and ERK, several kinetic simulation models have been developed. However, a large number of parameters that are essential for...
7.
Itoh R, Kurokawa K, Fujioka A, Sharma A, Mayer B, Matsuda M
Exp Cell Res
. 2005 Jun;
307(1):142-52.
PMID: 15922734
Epidermal growth factor (EGF) receptor plays a pivotal role in a variety of cellular functions, such as proliferation, differentiation, and migration. To monitor the EGF receptor (EGFR) activity in living...
8.
Kurokawa K, Itoh R, Yoshizaki H, Nakamura Y, Matsuda M
Mol Biol Cell
. 2003 Dec;
15(3):1003-10.
PMID: 14699061
A major function of Rho-family GTPases is to regulate the organization of the actin cytoskeleton; filopodia, lamellipodia, and stress fiber are regarded as typical phenotypes of the activated Cdc42, Rac,...
9.
Yoshizaki H, Ohba Y, Kurokawa K, Itoh R, Nakamura T, Mochizuki N, et al.
J Cell Biol
. 2003 Jul;
162(2):223-32.
PMID: 12860967
Rho-family GTPases regulate many cellular functions. To visualize the activity of Rho-family GTPases in living cells, we developed fluorescence resonance energy transfer (FRET)-based probes for Rac1 and Cdc42 previously (Itoh,...
10.
Itoh R, Kurokawa K, Ohba Y, Yoshizaki H, Mochizuki N, Matsuda M
Mol Cell Biol
. 2002 Aug;
22(18):6582-91.
PMID: 12192056
Rho family G proteins, including Rac and Cdc42, regulate a variety of cellular functions such as morphology, motility, and gene expression. We developed fluorescent resonance energy transfer-based probes which monitored...