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Rebecca N Nix

Explore the profile of Rebecca N Nix including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 218
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Recent Articles
1.
Xu Y, Liu X, Saunders M, Pearce S, Foulks J, Parnell K, et al.
Bioorg Med Chem Lett . 2013 Dec; 24(2):515-9. PMID: 24374270
Activators of the pyruvate kinase M2 (PKM2) are currently attracting significant interest as potential anticancer therapies. They may achieve a novel antiproliferation response in cancer cells through modulation of the...
2.
Wrobel C, Geiger T, Nix R, Robitaille A, Weigand S, Cervantes A, et al.
Virus Res . 2013 Oct; 178(2):314-27. PMID: 24075898
LMP-1 is a constitutively active Tumor Necrosis Factor Receptor analog encoded by Epstein-Barr virus. LMP-1 activation correlates with oligomerization and raft localization, but direct evidence of LMP-1 oligomers is limited....
3.
Parnell K, Foulks J, Nix R, Clifford A, Bullough J, Luo B, et al.
Mol Cancer Ther . 2013 May; 12(8):1453-60. PMID: 23720766
Inactivation of the M2 form of pyruvate kinase (PKM2) in cancer cells is associated with increased tumorigenicity. To test the hypothesis that tumor growth may be inhibited through the PKM2...
4.
Foulks J, Parnell K, Nix R, Chau S, Swierczek K, Saunders M, et al.
J Biomol Screen . 2011 Oct; 17(1):2-17. PMID: 21965114
Epigenetic modification of DNA leads to changes in gene expression. DNA methyltransferases (DNMTs) comprise a family of nuclear enzymes that catalyze the methylation of CpG dinucleotides, resulting in an epigenetic...
5.
Brown D, McCoy M, Pilonieta M, Nix R, Detweiler C
PLoS One . 2010 Mar; 5(2):e9441. PMID: 20195482
Hemophagocytic lymphohistiocytosis (HLH) is a hyper-inflammatory clinical syndrome associated with neoplastic disorders especially lymphoma, autoimmune conditions, and infectious agents including bacteria, viruses, protozoa and fungi. In both human and veterinary...
6.
Nix R, Altschuler S, Henson P, Detweiler C
PLoS Pathog . 2007 Dec; 3(12):e193. PMID: 18085823
Salmonella enterica subspecies can establish persistent, systemic infections in mammals, including human typhoid fever. Persistent S. enterica disease is characterized by an initial acute infection that develops into an asymptomatic...