Rebecca Klein
Overview
Explore the profile of Rebecca Klein including associated specialties, affiliations and a list of published articles.
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25
Citations
348
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Recent Articles
1.
Friker L, Perwein T, Waha A, Dorner E, Klein R, Blattner-Johnson M, et al.
Acta Neuropathol
. 2025 Feb;
149(1):11.
PMID: 39894875
Pediatric high-grade glioma (pedHGG) can occur as first manifestation of cancer predisposition syndromes resulting from pathogenic germline variants in the DNA mismatch repair (MMR) genes MSH2, MSH6, MLH1, and PMS2....
2.
Klein R, Judson M, Barkes B, Maier L, Zeigler J, Culver D, et al.
Sarcoidosis Vasc Diffuse Lung Dis
. 2023 Mar;
40(1):e2023010.
PMID: 36975058
Introduction: activity tracker device usage can help analyze the impact of disease state and therapy on patients in clinical practice. factors such as age, race, and gender may contribute to...
3.
Adams G, Pall P, Grauer S, Zhou X, Ballard J, Vavrek M, et al.
J Med Chem
. 2021 Dec;
65(1):485-496.
PMID: 34931831
Inhibitor cystine knot peptides, derived from venom, have evolved to block ion channel function but are often toxic when dosed at pharmacologically relevant levels . The article describes the design...
4.
Roecker A, Layton M, Pero J, Kelly 3rd M, Greshock T, Kraus R, et al.
ACS Med Chem Lett
. 2021 Jun;
12(6):1038-1049.
PMID: 34141090
The voltage-gated sodium channel Na1.7 continues to be a high-profile target for the treatment of various pain afflictions due to its strong human genetic validation. While isoform selective molecules have...
5.
Weise F, Vijay V, Jacobson A, Schoonover R, Groom R, Horgan J, et al.
PeerJ
. 2017 Dec;
5:e4096.
PMID: 29250465
Assessing the numbers and distribution of threatened species is a central challenge in conservation, often made difficult because the species of concern are rare and elusive. For some predators, this...
6.
Rosenbaum B, Klein R, Hagan P, Seadey M, Quarcoo N, Hoffmann R, et al.
Pan Afr Med J
. 2017 May;
26:125.
PMID: 28533848
Introduction: Ghana is currently developing its provision of dermatology services. Epidemiologic studies of the skin diseases seen by Ghanaian dermatologists are needed to guide these efforts. We aimed to describe...
7.
Pero J, Rossi M, Lehman H, Kelly 3rd M, Mulhearn J, Wolkenberg S, et al.
Bioorg Med Chem Lett
. 2017 May;
27(12):2683-2688.
PMID: 28465103
Studies on human genetics have suggested that inhibitors of the Na1.7 voltage-gated sodium channel hold considerable promise as therapies for the treatment of chronic pain syndromes. Herein, we report novel,...
8.
Roecker A, Egbertson M, Jones K, Gomez R, Kraus R, Li Y, et al.
Bioorg Med Chem Lett
. 2017 Apr;
27(10):2087-2093.
PMID: 28389149
The voltage-gated sodium channel Na1.7 is a genetically validated target for the treatment of pain with gain-of-function mutations in man eliciting a variety of painful disorders and loss-of-function mutations affording...
9.
Durant S, Mitchell N, Groom R, Pettorelli N, Ipavec A, Jacobson A, et al.
Proc Natl Acad Sci U S A
. 2016 Dec;
114(3):528-533.
PMID: 28028225
Establishing and maintaining protected areas (PAs) are key tools for biodiversity conservation. However, this approach is insufficient for many species, particularly those that are wide-ranging and sparse. The cheetah Acinonyx...
10.
Hubel T, Shotton J, Wilshin S, Horgan J, Klein R, McKenna R, et al.
PLoS One
. 2016 Dec;
11(12):e0166864.
PMID: 27926915
Animals navigate their environment using a variety of senses and strategies. This multiplicity enables them to respond to different navigational requirements resulting from habitat, scale and purpose. One of the...