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Rebecca E Johnson

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Articles 12
Citations 345
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Recent Articles
1.
Philbin S, Johnson R, Pedamallu H, Carroll A, Ekong A, Lazar D, et al.
Ethn Dis . 2024 Jun; DECIPHeR(Spec Issue):60-67. PMID: 38846723
Objectives: Hypertension is associated with high morbidity and mortality. The complications of hypertension disproportionately impact African American residents in Chicago's South Side neighborhood. To inform the implementation of an evidence-based...
2.
Keylor M, Gulati A, Kattar S, Johnson R, Chau R, Margrey K, et al.
J Med Chem . 2021 Dec; 65(1):838-856. PMID: 34967623
The leucine-rich repeat kinase 2 (LRRK2) protein has been genetically and functionally linked to Parkinson's disease (PD), a disabling and progressive neurodegenerative disorder whose current therapies are limited in scope...
3.
Johnson R, Ree H, Hartmann M, Lang L, Sawano S, Sarpong R
J Am Chem Soc . 2019 Feb; 141(6):2233-2237. PMID: 30702879
The first synthesis of a pentacyclic ambiguine (ambiguine P) is reported. The synthesis takes advantage of sequential alkylations of an indole core to rapidly construct the pentacyclic framework of the...
4.
Johnson R, Oyebode O, Walker S, Knowles E, Robertson W
BMC Res Notes . 2018 May; 11(1):325. PMID: 29784021
Objective: The Eat Well Move More (EWMM) family and child weight management service is a 12-week intervention integrating healthy eating and physical activity education and activities for families and children...
5.
de Rond T, Stow P, Eigl I, Johnson R, Chan L, Goyal G, et al.
Nat Chem Biol . 2017 Sep; 13(11):1155-1157. PMID: 28892091
Prodiginines, which are tripyrrole alkaloids displaying a wide array of bioactivities, occur as linear and cyclic congeners. Identification of an unclustered biosynthetic gene led to the discovery of the enzyme...
6.
Al-Khudairy L, Loveman E, Colquitt J, Mead E, Johnson R, Fraser H, et al.
Cochrane Database Syst Rev . 2017 Jun; 6:CD012691. PMID: 28639320
Background: Adolescent overweight and obesity has increased globally, and can be associated with short- and long-term health consequences. Modifying known dietary and behavioural risk factors through behaviour changing interventions (BCI)...
7.
Loveman E, Al-Khudairy L, Johnson R, Robertson W, Colquitt J, Mead E, et al.
Cochrane Database Syst Rev . 2015 Dec; (12):CD012008. PMID: 26690844
Background: Child and adolescent overweight and obesity have increased globally, and are associated with short- and long-term health consequences. Objectives: To assess the efficacy of diet, physical activity and behavioural...
8.
Johnson R, de Rond T, Lindsay V, Keasling J, Sarpong R
Org Lett . 2015 Jun; 17(14):3474-7. PMID: 26114660
The enantiomers of the natural product cycloprodigiosin were prepared using an expedient five-step synthetic sequence that takes advantage of a Schöllkopf-Barton-Zard (SBZ) pyrrole annulation with a chiral isocyanoacetate and a...
9.
Hercbergs A, Johnson R, Ashur-Fabian O, Garfield D, Davis P
Oncologist . 2014 Nov; 20(1):72-6. PMID: 25410096
Background: Clinical studies have shown that interventional lowering of serum free thyroxine (FT4) may be associated with extended survival in patients with some terminal cancers. The report of success with...
10.
Hodous B, Geuns-Meyer S, Hughes P, Albrecht B, Bellon S, Caenepeel S, et al.
Bioorg Med Chem Lett . 2007 Mar; 17(10):2886-9. PMID: 17350837
A novel class of selective Tie-2 inhibitors was derived from a multi-kinase inhibitor 1. By reversing the amide connectivity and incorporating aminotriazine or aminopyridine hinge-binding moieties, excellent Tie-2 potency and...