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Rebecca C Hull

Explore the profile of Rebecca C Hull including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 37
Followers 0
Related Specialties
Pulmonary Medicine
Biochemistry
Pharmacology
Top 10 Co-Authors
Alison M Condliffe
James D Chalmers
Chloe Hughes
Thomas Pembridge
Holly R Keir
Merete B Long
Amy Gilmour
Yan Hui Giam
Hani Abo-Leyah
Simon J Foster
Published In
ERJ Open Res
Int J Mol Sci
Lancet Respir Med
Chest
Antimicrob Agents Chemother
Affiliations
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Recent Articles
1.
A serum calprotectin lateral flow test as an inflammatory and prognostic marker in acute lung infection: a prospective observational study
Gilmour A, Hughes C, Giam Y, Hull R, Pembridge T, Abo-Leyah H, et al.
ERJ Open Res . 2024 Jun; 10(3). PMID: 38887680
https://bit.ly/48e1BIv.
2.
SFX-01 in hospitalised patients with community-acquired pneumonia during the COVID-19 pandemic: a double-blind, randomised, placebo-controlled trial
Long M, Abo-Leyah H, Giam Y, Vadiveloo T, Hull R, Keir H, et al.
ERJ Open Res . 2024 Mar; 10(2). PMID: 38469377
Introduction: Sulforaphane can induce the transcription factor, Nrf2, promoting antioxidant and anti-inflammatory responses. In this study, hospitalised patients with community-acquired pneumonia (CAP) were treated with stabilised synthetic sulforaphane (SFX-01) to...
3.
Antibiotics Limit Adaptation of Drug-Resistant Staphylococcus aureus to Hypoxia
Hull R, Wright R, Sayers J, Sutton J, Rzaska J, Foster S, et al.
Antimicrob Agents Chemother . 2022 Nov; 66(12):e0092622. PMID: 36409116
Bacterial pathogens are confronted with a range of challenges at the site of infection, including exposure to antibiotic treatment and harsh physiological conditions, that can alter the fitness benefits and...
4.
Dipeptidyl peptidase-1 inhibition in patients hospitalised with COVID-19: a multicentre, double-blind, randomised, parallel-group, placebo-controlled trial
Keir H, Long M, Abo-Leyah H, Giam Y, Vadiveloo T, Pembridge T, et al.
Lancet Respir Med . 2022 Sep; 10(12):1119-1128. PMID: 36075243
Background: Neutrophil serine proteases are involved in the pathogenesis of COVID-19 and increased serine protease activity has been reported in severe and fatal infection. We investigated whether brensocatib, an inhibitor...
5.
Enhanced neutrophil extracellular trap formation in COVID-19 is inhibited by the protein kinase C inhibitor ruboxistaurin
Dowey R, Cole J, Thompson A, Hull R, Huang C, Whatmore J, et al.
ERJ Open Res . 2022 Apr; 8(2). PMID: 35382002
Background: Neutrophil extracellular traps (NETs) are web-like DNA and protein lattices which are expelled by neutrophils to trap and kill pathogens, but which cause significant damage to the host tissue....
6.
Sputum Proteomics in Nontuberculous Mycobacterial Lung Disease
Hull R, Huang J, Barton A, Keir H, Ellis H, Cookson W, et al.
Chest . 2021 Nov; 161(5):1180-1191. PMID: 34838525
Background: Nontuberculous mycobacterial (NTM) infections are difficult to diagnose and treat. Biomarkers to identify patients with active infection or at risk of disease progression would have clinical utility. Sputum is...
7.
The Impact of Hypoxia on the Host-Pathogen Interaction between Neutrophils and
Hajdamowicz N, Hull R, Foster S, Condliffe A
Int J Mol Sci . 2019 Nov; 20(22). PMID: 31703398
Neutrophils are key to host defence, and impaired neutrophil function predisposes to infection with an array of pathogens, with a common and sometimes life-threatening problem in this setting. Both infiltrating...