Raymond S H Yang
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Explore the profile of Raymond S H Yang including associated specialties, affiliations and a list of published articles.
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45
Citations
383
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Recent Articles
1.
Lohitnavy M, Lu Y, Lohitnavy O, Yang R
Annu Int Conf IEEE Eng Med Biol Soc
. 2017 Oct;
2017:2728-2731.
PMID: 29060462
An updated physiologically-based pharmacokinetic (PBPK) model of methotrexate (MTX) was built based on an earlier model developed by Bischoff et al. (1971). MTX has been known to be a substrate...
2.
Lin Z, Jaberi-Douraki M, He C, Jin S, Yang R, Fisher J, et al.
Toxicol Sci
. 2017 Apr;
158(1):23-35.
PMID: 28402537
Many physiologically based pharmacokinetic (PBPK) models for environmental chemicals, drugs, and nanomaterials have been developed to aid risk and safety assessments using acslX. However, acslX has been rendered sunset since...
3.
Lehmann G, Verner M, Luukinen B, Henning C, Assimon S, LaKind J, et al.
Crit Rev Toxicol
. 2014 Jul;
44(7):600-17.
PMID: 25068490
Lipophilic persistent environmental chemicals (LPECs) have the potential to accumulate within a woman's body lipids over the course of many years prior to pregnancy, to partition into human milk, and...
4.
Weijs L, Roach A, Yang R, McDougall R, Lyons M, Housand C, et al.
Chemosphere
. 2013 Oct;
94:91-6.
PMID: 24080004
Physiologically based pharmacokinetic (PBPK) models for wild animal populations such as marine mammals typically have a high degree of model uncertainty and variability due to the scarcity of information and...
5.
Weijs L, Yang R, Das K, Covaci A, Blust R
Environ Sci Technol
. 2013 Apr;
47(9):4365-74.
PMID: 23560461
Physiologically based pharmacokinetic (PBPK) modeling in marine mammals is a challenge because of the lack of parameter information and the ban on exposure experiments. To minimize uncertainty and variability, parameter...
6.
Lyons M, Reisfeld B, Yang R, Lenaerts A
Antimicrob Agents Chemother
. 2013 Jan;
57(4):1763-71.
PMID: 23357766
One problem associated with regimen-based development of antituberculosis (anti-TB) drugs is the difficulty of a systematic and thorough in vivo evaluation of the large number of possible regimens that arise...
7.
Wang N, Rice G, Teuschler L, Colman J, Yang R
J Toxicol
. 2012 Apr;
2012:410143.
PMID: 22496687
Both the Massachusetts Department of Environmental Protection (MADEP) and the Total Petroleum Hydrocarbon Criteria Working Group (TPHCWG) developed fraction-based approaches for assessing human health risks posed by total petroleum hydrocarbon...
8.
Weijs L, Covaci A, Yang R, Das K, Blust R
Environ Pollut
. 2012 Feb;
163:134-41.
PMID: 22325441
Due to migration of harbour porpoises towards more polluted areas like the North Sea and their sensitivity towards pollution, there is a need for proper conservation measures for this species....
9.
Weijs L, Covaci A, Yang R, Das K, Blust R
Toxicol Appl Pharmacol
. 2011 Aug;
256(2):136-45.
PMID: 21851832
In the last decade, physiologically based pharmacokinetic (PBPK) models have increasingly been developed to explain the kinetics of environmental pollutants in wildlife. For marine mammals specifically, these models provide a...
10.
Reisfeld B, Yang R
Environ Toxicol Pharmacol
. 2011 Jul;
18(2):173-9.
PMID: 21782746
In this paper, we describe a modeling approach to predict the interlinked pathways and kinetics resulting from CYP2E1-mediated metabolism of both pure species and chemical mixtures. This approach is based...