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Raymond D Lund

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Articles 16
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Recent Articles
1.
Lu B, Wang S, Francis P, Li T, Gamm D, Capowski E, et al.
Invest Ophthalmol Vis Sci . 2009 Dec; 51(4):2269-76. PMID: 19959642
Purpose. Usher's syndrome is a combined deafness and blindness disorder caused by mutations in several genes with functions in both the retina and the ear. Here the authors studied morphologic...
2.
Francis P, Wang S, Zhang Y, Brown A, Hwang T, McFarland T, et al.
Invest Ophthalmol Vis Sci . 2009 Feb; 50(7):3425-31. PMID: 19234356
Purpose: Cell-based therapy rescues retinal structure and function in rodent models of retinal disease, but translation to clinical practice will require more information about the consequences of transplantation in an...
3.
Wang S, Girman S, Lu B, Bischoff N, Holmes T, Shearer R, et al.
Invest Ophthalmol Vis Sci . 2008 Jun; 49(7):3201-6. PMID: 18579765
Purpose: As a follow-up to previous studies showing that human cortical neural progenitor cells (hNPC(ctx)) can sustain vision for at least 70 days after injection into the subretinal space of...
4.
Wang S, Lu B, Girman S, Holmes T, Bischoff N, Lund R
Invest Ophthalmol Vis Sci . 2008 Jan; 49(1):416-21. PMID: 18172120
Purpose: It is well documented that grafting of cells in the subretinal space of Royal College of Surgeons (RCS) rats limits deterioration of vision and loss of photoreceptors if performed...
5.
McGill T, Prusky G, Douglas R, Yasumura D, Matthes M, Nune G, et al.
Invest Ophthalmol Vis Sci . 2007 Dec; 48(12):5756-66. PMID: 18055829
Purpose: CNTF is a neuroprotective agent for retinal degenerations that can cause reduced electroretinogram (ERG) amplitudes. The goal of the present study was to determine the effects of intraocular delivery...
6.
Pinilla I, Cuenca N, Sauve Y, Wang S, Lund R
Exp Eye Res . 2007 Jul; 85(3):381-92. PMID: 17662715
We have examined how transplantation of an RPE cell line to the subretinal space of RCS rats affects the distribution of synaptic connectivity markers in the outer plexiform layer of...
7.
Gamm D, Wang S, Lu B, Girman S, Holmes T, Bischoff N, et al.
PLoS One . 2007 Mar; 2(3):e338. PMID: 17396165
Background: A promising clinical application for stem and progenitor cell transplantation is in rescue therapy for degenerative diseases. This strategy seeks to preserve rather than restore host tissue function by...
8.
McGill T, Lund R, Douglas R, Wang S, Lu B, Silver B, et al.
Invest Ophthalmol Vis Sci . 2007 Mar; 48(4):1906-12. PMID: 17389527
Purpose: To evaluate the efficacy of immunologically compatible Schwann cells transplanted without immunosuppression in the RCS rat retina to preserve vision. Methods: Syngeneic (dystrophic RCS) Schwann cells harvested from sciatic...
9.
Lund R, Wang S, Lu B, Girman S, Holmes T, Sauve Y, et al.
Stem Cells . 2006 Oct; 25(3):602-11. PMID: 17053209
Progressive photoreceptor degeneration resulting from genetic and other factors is a leading and largely untreatable cause of blindness worldwide. The object of this study was to find a cell type...
10.
Lund R, Wang S, Klimanskaya I, Holmes T, Ramos-Kelsey R, Lu B, et al.
Cloning Stem Cells . 2006 Oct; 8(3):189-99. PMID: 17009895
Embryonic stem cells promise to provide a well-characterized and reproducible source of replacement tissue for human clinical studies. An early potential application of this technology is the use of retinal...