Raymond A Koski
Overview
Explore the profile of Raymond A Koski including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
1304
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0
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Recent Articles
1.
Doyle H, Gee R, Masters T, Gee C, Booth C, Peterson-Roth E, et al.
Transl Oncol
. 2021 Aug;
14(11):101205.
PMID: 34419682
Epidermal Growth Factor Receptor (EGFR) is overexpressed on a number of human cancers, and often is indicative of a poor outcome. Treatment of EGFR/HER2 overexpressing cancers includes monoclonal antibody therapy...
2.
Cirillo P, Asojo O, Khire U, Lee Y, Mootien S, Hegan P, et al.
ACS Med Chem Lett
. 2020 Oct;
11(10):1843-1847.
PMID: 33062162
Human Macrophage Migration Inhibitory Factor (MIF) is a trimeric cytokine implicated in a number of inflammatory and autoimmune diseases and cancer. We previously reported that the dye p425 (Chicago Sky...
3.
Doyle H, Koski R, Bonafe N, Bruck R, Tagliatela S, Gee R, et al.
Cancer Immunol Immunother
. 2018 Jul;
67(10):1559-1569.
PMID: 30056598
Current treatments for tumors expressing epidermal growth factor receptor (EGFR) include anti-EGFR monoclonal antibodies, often used in conjunction with the standard chemotherapy, radiation therapy, or other EGFR inhibitors. While monoclonal...
4.
Asojo O, Nelson S, Mootien S, Lee Y, Rezende W, Hyman D, et al.
Acta Crystallogr D Biol Crystallogr
. 2014 Jul;
70(Pt 7):1922-33.
PMID: 25004969
Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among hospitalized patients. C. difficile is frequently associated with antibiotic treatment, and causes diseases ranging from...
5.
Narasimhan S, Perez O, Mootien S, DePonte K, Koski R, Fikrig E, et al.
PLoS One
. 2013 Jul;
8(7):e68012.
PMID: 23874485
Ixodes scapularis, the black-legged tick, vectors several human pathogens including Borrelia burgdorferi, the agent of Lyme disease in North America. Pathogen transmission to the vertebrate host occurs when infected ticks...
6.
Lee Y, Mootien S, Shoen C, DeStefano M, Cirillo P, Asojo O, et al.
Biochem Pharmacol
. 2013 May;
86(2):222-30.
PMID: 23680030
The genus Mycobacterium includes non-pathogenic species such as M. smegmatis, and pathogenic species such as M. tuberculosis, the causative agent of tuberculosis (TB). Treatment of TB requires a lengthy regimen...
7.
Sultana H, Neelakanta G, Foellmer H, Montgomery R, Anderson J, Koski R, et al.
J Immunol
. 2012 Aug;
189(6):3150-8.
PMID: 22896629
Semaphorin 7A (Sema7A) is a membrane-associated/secreted protein that plays an essential role in connecting the vertebrate neuronal and immune systems. However, the role of Sema7A has not been elucidated in...
8.
Bai F, Asojo O, Cirillo P, Ciustea M, Ledizet M, Aristoff P, et al.
J Biol Chem
. 2012 Jul;
287(36):30653-63.
PMID: 22782901
Macrophage migration inhibitory factor (MIF) is a catalytic cytokine and an upstream mediator of the inflammatory pathway. MIF has broad regulatory properties, dysregulation of which has been implicated in the...
9.
Ciustea M, Mootien S, Rosato A, Perez O, Cirillo P, Yeung K, et al.
Biochem Pharmacol
. 2011 Dec;
83(3):368-77.
PMID: 22146584
Methicillin-resistant Staphylococcus aureus (MRSA) is a human pathogen and a major cause of hospital-acquired infections. New antibacterial agents that have not been compromised by bacterial resistance are needed to treat...
10.
Asojo O, Koski R, Bonafe N
Acta Crystallogr D Biol Crystallogr
. 2011 Sep;
67(Pt 10):847-55.
PMID: 21931216
Human glioma pathogenesis-related protein 1 (GLIPR1) is a membrane protein that is highly upregulated in brain cancers but is barely detectable in normal brain tissue. GLIPR1 is composed of a...