Ravshan Z Sabirov
Overview
Explore the profile of Ravshan Z Sabirov including associated specialties, affiliations and a list of published articles.
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42
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941
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Recent Articles
11.
Rustamova S, Tsiferova N, Khamidova O, Kurbannazarova R, Merzlyak P, Khushbaktova Z, et al.
Pharmacol Rep
. 2019 Oct;
71(6):1079-1087.
PMID: 31629088
Background: Cell volume regulation and volume-regulated anion channels are critical for cell survival in non-isosmotic conditions, and dysregulation of this system is detrimental. Although genes and proteins underlying this basic...
12.
Okada Y, Numata T, Sato-Numata K, Sabirov R, Liu H, Mori S, et al.
Curr Top Membr
. 2019 Jun;
83:205-283.
PMID: 31196606
Two types of anion channels are directly activated by osmotic swelling and are involved in the regulatory volume decrease (RVD) in most types of mammalian cells, and they include the...
13.
Okada Y, Okada T, Sato-Numata K, Islam M, Ando-Akatsuka Y, Numata T, et al.
Pharmacol Rev
. 2018 Dec;
71(1):49-88.
PMID: 30573636
There are a number of mammalian anion channel types associated with cell volume changes. These channel types are classified into two groups: volume-activated anion channels (VAACs) and volume-correlated anion channels...
14.
Okada Y, Okada T, Islam M, Sabirov R
Curr Top Membr
. 2018 Sep;
81:125-176.
PMID: 30243431
An elaborate volume regulation system based on interplay of ion channels and transporters was evolved to cope with constant osmotic challenges caused by intensive metabolism, transport and other physiological/pathophysiological events....
15.
Sabirov R, Merzlyak P, Okada T, Islam M, Uramoto H, Mori T, et al.
EMBO J
. 2017 Oct;
36(22):3309-3324.
PMID: 29046334
The maxi-anion channels (MACs) are expressed in cells from mammals to amphibians with ~60% exhibiting a phenotype called Maxi-Cl. Maxi-Cl serves as the most efficient pathway for regulated fluxes of...
16.
Okada T, Islam M, Tsiferova N, Okada Y, Sabirov R
Channels (Austin)
. 2016 Nov;
11(2):109-120.
PMID: 27764579
The broadly expressed volume-sensitive outwardly rectifying anion channel (VSOR, also called VRAC) plays essential roles in cell survival and death. Recent findings have suggested that LRRC8A is a core component...
17.
Sato-Numata K, Numata T, Inoue R, Sabirov R, Okada Y
Channels (Austin)
. 2016 Sep;
11(2):167-172.
PMID: 27579940
Volume- and acid-sensitive outwardly rectifying anion channels (VSOR and ASOR) activated by swelling and acidification exhibit voltage-dependent inactivation and activation time courses, respectively. Recently, LRRC8A and some paralogs were shown...
18.
Sabirov R, Merzlyak P, Islam M, Okada T, Okada Y
Pflugers Arch
. 2016 Jan;
468(3):405-20.
PMID: 26733413
The maxi-anion channels (MACs) with a unitary conductance of 200-500 pS are detected in virtually every part of the whole body and found in cells from mammals to amphibia. The...
19.
Sabirov R, Kurbannazarova R, Melanova N, Okada Y
PLoS One
. 2013 Feb;
8(1):e55646.
PMID: 23383255
Glutathione (GSH) is a negatively charged tripeptide, which is a major determinant of the cellular redox state and defense against oxidative stress. It is assembled inside and degraded outside the...
20.
Islam M, Uramoto H, Okada T, Sabirov R, Okada Y
Am J Physiol Cell Physiol
. 2012 Jul;
303(9):C924-35.
PMID: 22785119
The maxi-anion channel plays a classically recognized role in controlling the membrane potential through the chloride conductance. It also has novel functions as a regulated pathway for the release of...