Ravindra N Singh
Overview
Explore the profile of Ravindra N Singh including associated specialties, affiliations and a list of published articles.
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Articles
57
Citations
2014
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Recent Articles
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Ottesen E, Singh N, Seo J, Singh R
Front Neurosci
. 2024 Aug;
18():1412893.
PMID: 39086841
Introduction: The U1 small nuclear RNA (snRNA) forms ribonucleoprotein particles (RNPs) such as U1 snRNP and U1-TAF15 snRNP. U1 snRNP is one of the most studied RNPs due to its...
3.
Luo D, Ottesen E, Lee J, Singh R
Sci Rep
. 2024 May;
14(1):10442.
PMID: 38714739
Spinal muscular atrophy (SMA) genes, SMN1 and SMN2 (hereinafter referred to as SMN1/2), produce multiple circular RNAs (circRNAs), including C2A-2B-3-4 that encompasses early exons 2A, 2B, 3 and 4. C2A-2B-3-4...
4.
Ottesen E, Singh R
Neurosci Insights
. 2024 Feb;
19():26331055241233596.
PMID: 38379891
Spinal muscular atrophy (SMA) is treated by increasing the level of Survival Motor Neuron (SMN) protein through correction of exon 7 skipping or exogenous expression of SMN through gene therapy....
5.
Ottesen E, Seo J, Luo D, Singh N, Singh R
Nucleic Acids Res
. 2024 Jan;
52(7):3547-3571.
PMID: 38214229
Here we report a Survival Motor Neuron 2 (SMN2) super minigene, SMN2Sup, encompassing its own promoter, all exons, their flanking intronic sequences and the entire 3'-untranslated region. We confirm that...
6.
Ottesen E, Singh N, Luo D, Kaas B, Gillette B, Seo J, et al.
Nucleic Acids Res
. 2023 Apr;
51(12):5948-5980.
PMID: 37026480
Designing an RNA-interacting molecule that displays high therapeutic efficacy while retaining specificity within a broad concentration range remains a challenging task. Risdiplam is an FDA-approved small molecule for the treatment...
7.
Singh N, OLeary C, Eich T, Moss W, Singh R
Front Mol Biosci
. 2022 Jul;
9:928581.
PMID: 35847983
Humans contain two nearly identical copies of genes, and . Deletion or mutation of causes spinal muscular atrophy (SMA), one of the leading genetic diseases associated with infant mortality. is...
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9.
Suryanarayan A, Cubas M, Craig O, Heron C, Shinde V, Singh R, et al.
J Archaeol Sci
. 2021 Feb;
125:105291.
PMID: 33519031
This paper presents novel insights into the archaeology of food in ancient South Asia by using lipid residue analysis to investigate what kinds of foodstuffs were used in ceramic vessels...
10.
Singh N, Hoffman S, Reddi P, Singh R
Biochim Biophys Acta Mol Basis Dis
. 2021 Jan;
1867(4):166063.
PMID: 33412266
Spinal muscular atrophy (SMA) is one of the major genetic disorders associated with infant mortality. More than 90% of cases of SMA result from deletions of or mutations in the...