Ravindra K Hajela
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Explore the profile of Ravindra K Hajela including associated specialties, affiliations and a list of published articles.
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10
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93
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Recent Articles
1.
Tsai T, Yuan Y, Hajela R, Philips S, Atchison W
Neurotoxicology
. 2016 Oct;
60:161-170.
PMID: 27720918
Early onset effects of methylmercury (MeHg) on recombinant αβγ or αβγ subunit-containing GABA receptors were examined. These are two of the most prevalent receptor types found in cerebellum-a consistent target...
2.
Hajela R, Huntoon K, Atchison W
Muscle Nerve
. 2014 May;
51(2):176-84.
PMID: 24862203
Introduction: Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune presynaptic neuromuscular disorder. Autoantibodies against subunits of voltage-gated calcium channels (VGCCs) associated with acetylcholine release are thought to cause LEMS. Methods: HEK293...
3.
Johnson F, Yuan Y, Hajela R, Chitrakar A, Parsell D, Atchison W
J Pharmacol Exp Ther
. 2011 May;
338(2):518-27.
PMID: 21586603
Mice expressing the human Cu(2+)/Zn(2+) superoxide dismutase 1 (hSOD1) gene mutation (hSOD1(G93A); G93A) were exposed to methylmercury (MeHg) at concentrations that did not cause overt motor dysfunction. We hypothesized that...
4.
Herden C, Pardo N, Hajela R, Yuan Y, Atchison W
J Pharmacol Exp Ther
. 2007 Nov;
324(2):517-28.
PMID: 17977981
Cerebellar granule cells are particularly sensitive to inhibition by methylmercury (MeHg) on GABA(A) receptor function. This is manifested as a more rapid block of inhibitory postsynaptic currents/inhibitory postsynaptic potentials than...
5.
Sheng Z, Peng S, Wang C, Li H, Hajela R, Wang Y, et al.
J Pharmacol Exp Ther
. 2007 Apr;
322(1):155-65.
PMID: 17400890
Quinolone(s) (QNs) is widely used in infection therapy due to its good antimicrobial characteristics. However, QNs-induced arthropathy of immature animals has led to restrictions on the therapeutic use of these...
6.
Pardo N, Hajela R, Atchison W
J Pharmacol Exp Ther
. 2006 Sep;
319(3):1009-20.
PMID: 16982704
The mutation in the alpha(1A) subunit gene of the P/Q-type (Ca(v)2.1) Ca(2+) channel present in tottering (tg) mice causes ataxia and motor seizures that resemble absence epilepsy in humans. P/Q-type...
7.
Peng S, Hajela R, Atchison W
Brain Res
. 2005 May;
1045(1-2):116-23.
PMID: 15910769
Mechanical forces can alter the gating of several kinds of ion channels in many types of cells, but the mechanisms underlying the mechanosensitivity are not clearly understood. To date, there...
8.
Hajela R, Peng S, Atchison W
J Pharmacol Exp Ther
. 2003 Jun;
306(3):1129-36.
PMID: 12805476
Expression cDNA clones of alpha1B-1 or alpha1E-3 subunits coding for human neuronal N-(Cav2.2) or R-subtype (Cav2.3) Ca2+ channels, respectively, was combined with alpha2-bdelta and beta3-a Ca2+ channel subunits, and transfected...
9.
Peng S, Hajela R, Atchison W
Mol Pharmacol
. 2002 Nov;
62(6):1418-30.
PMID: 12435810
Lead (Pb(2+)) is a well-known inhibitor of voltage-dependent Ca(2+) channels in their native environments in several types of cells. However, its effects on discrete Ca(2+) channel phenotypes in isolation have...
10.
Peng S, Hajela R, Atchison W
J Pharmacol Exp Ther
. 2002 Jul;
302(2):424-32.
PMID: 12130699
Methylmercury (MeHg) disrupts the function of native, high voltage-activated neuronal Ca(2+) channels in several types of cells. However, the effects of MeHg on isolated Ca(2+) channel phenotypes have not been...