Ravikanth Metlapally
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Explore the profile of Ravikanth Metlapally including associated specialties, affiliations and a list of published articles.
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22
Citations
581
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Recent Articles
1.
Wang K, Metlapally R, Wildsoet C
Curr Eye Res
. 2017 Jan;
42(6):857-863.
PMID: 28094579
Purpose: The ocular dimensional changes in myopia reflect increased scleral remodeling, and in high myopia, loss of scleral integrity leads to biomechanical weakening and continued scleral creep. As integrins, a...
2.
Metlapally R, Park H, Chakraborty R, Wang K, Tan C, Light J, et al.
Invest Ophthalmol Vis Sci
. 2016 Nov;
57(14):6089-6097.
PMID: 27832275
Purpose: MicroRNA (miRNAs) have been previously implicated in scleral remodeling in normal eye growth. They have the potential to be therapeutic targets for prevention/retardation of exaggerated eye growth in myopia...
3.
Shen L, Melles R, Metlapally R, Barcellos L, Schaefer C, Risch N, et al.
Ophthalmology
. 2015 Aug;
123(1):92-101.
PMID: 26260281
Purpose: To evaluate the association between refractive error and the prevalence of glaucoma by race or ethnicity. Design: Cross-sectional study. Participants: Kaiser Permanente Northern California Health Plan members with refractive...
4.
Metlapally R, Gonzalez P, Hawthorne F, Tran-Viet K, Wildsoet C, Young T
PLoS One
. 2013 Nov;
8(10):e78984.
PMID: 24205357
Introduction: In human eyes, ocular enlargement/growth reflects active extracellular matrix remodeling of the outer scleral shell. Micro-RNAs are small non-coding RNAs that regulate gene expression by base pairing with target...
5.
Young T, Hawthorne F, Feng S, Luo X, St Germain E, Wang M, et al.
Exp Eye Res
. 2013 Sep;
116:265-78.
PMID: 24016867
To study growth and development of ocular tissues, gene expression patterns in normal human fetal versus adult eyes were compared. Human retina/retinal pigment epithelium, choroid, sclera, optic nerve* and cornea*...
6.
Tran-Viet K, Powell C, Barathi V, Klemm T, Maurer-Stroh S, Limviphuvadh V, et al.
Am J Hum Genet
. 2013 May;
92(5):820-6.
PMID: 23643385
Myopia, or near-sightedness, is an ocular refractive error of unfocused image quality in front of the retinal plane. Individuals with high-grade myopia (dioptric power greater than -6.00) are predisposed to...
7.
Tran-Viet K, Soler V, Quiette V, Powell C, Yanovitch T, Metlapally R, et al.
Mol Vis
. 2013 Apr;
19:759-66.
PMID: 23592912
Purpose: Stickler syndrome is an arthro-ophthalmopathy with phenotypic overlap with Wagner syndrome. The common Stickler syndrome type I is inherited as an autosomal dominant trait, with causal mutations in collagen...
8.
Hawthorne F, Feng S, Metlapally R, Li Y, Tran-Viet K, Guggenheim J, et al.
Invest Ophthalmol Vis Sci
. 2013 Feb;
54(3):2076-86.
PMID: 23422819
Purpose: Myopia, or nearsightedness, is a common ocular genetic disease for which over 20 candidate genomic loci have been identified. The high-grade myopia locus, MYP3, has been reported on chromosome...
9.
Lim S, Tran-Viet K, Yanovitch T, Freedman S, Klemm T, Call W, et al.
Am J Ophthalmol
. 2012 Dec;
155(3):508-517.e5.
PMID: 23218701
Purpose: To screen primary congenital glaucoma patients in the United States for sequence variants within the CYP1B1, LTBP2, and MYOC genes using Sanger and whole exome sequencing. Design: Retrospective case-control...
10.
Abbott D, Li Y, Guggenheim J, Metlapally R, Malecaze F, Calvas P, et al.
Mol Vis
. 2012 Apr;
18:720-9.
PMID: 22509102
Purpose: To investigate quantitative trait loci linked to refractive error, we performed a genome-wide quantitative trait linkage analysis using single nucleotide polymorphism markers and family data from five international sites....