Raquel C de Melo-Minardi
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Explore the profile of Raquel C de Melo-Minardi including associated specialties, affiliations and a list of published articles.
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20
Citations
160
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Recent Articles
1.
Moraes Dos Santos L, Gutembergue de Mendonca J, Jeronimo Gomes Lobo Y, Henrique Franca de Lima L, Bruno Rocha G, C de Melo-Minardi R
Sci Rep
. 2024 Sep;
14(1):22639.
PMID: 39349594
Molecular dynamics (MD) simulations produce a substantial volume of high-dimensional data, and traditional methods for analyzing these data pose significant computational demands. Advances in MD simulation analysis combined with deep...
2.
Bialves T, Bastos L, Parra J, Moyses M, Marques E, de Castro Pimenta A, et al.
Int J Biol Macromol
. 2024 Jun;
274(Pt 1):133283.
PMID: 38909731
Metastatic melanoma is highly aggressive and challenging, often leading to a grim prognosis. Its progression is swift, especially when mutations like BRAFV600E continuously activate pathways vital for cell growth and...
3.
Abreu A, Carvalho F, Mariano D, Bastos L, Silva J, de Oliveira L, et al.
Molecules
. 2024 Apr;
29(7).
PMID: 38611856
SARS-CoV-2 is the virus responsible for a respiratory disease called COVID-19 that devastated global public health. Since 2020, there has been an intense effort by the scientific community to develop...
4.
Horacio E, de Carvalho L, Pereira G, Abrahim M, Coelho M, De Jesus D, et al.
PLoS Comput Biol
. 2023 Dec;
19(12):e1011679.
PMID: 38127831
The article presents a framework for a Bioinformatics competition that focuses on 4 key aspects: structure, model, overview, and perspectives. Structure represents the organizational framework employed to coordinate the main...
5.
Salgado A, C de Melo-Minardi R, Giovanetti M, Veloso A, Morais-Rodrigues F, Adelino T, et al.
PLoS One
. 2022 Dec;
17(12):e0278982.
PMID: 36508435
Yellow fever virus (YFV) is the agent of the most severe mosquito-borne disease in the tropics. Recently, Brazil suffered major YFV outbreaks with a high fatality rate affecting areas where...
6.
da Silva A, Abreu A, Mariano D, Caixeta F, Santos F, Lage F, et al.
Front Bioinform
. 2022 Oct;
1:711463.
PMID: 36303729
Bioinformatics is a fast-evolving research field, requiring effective educational initiatives to bring computational knowledge to Life Sciences. Since 2017, an organizing committee composed of graduate students and postdoctoral researchers from...
7.
GRaSP-web: a machine learning strategy to predict binding sites based on residue neighborhood graphs
Santana C, Izidoro S, C de Melo-Minardi R, Tyzack J, Ribeiro A, Pires D, et al.
Nucleic Acids Res
. 2022 May;
50(W1):W392-W397.
PMID: 35524575
Proteins are essential macromolecules for the maintenance of living systems. Many of them perform their function by interacting with other molecules in regions called binding sites. The identification and characterization...
8.
Martins P, Santos L, Mariano D, Queiroz F, Bastos L, Gomes I, et al.
BMC Bioinformatics
. 2021 Jan;
22(1):1.
PMID: 33388027
Background: Protein-peptide interactions play a fundamental role in a wide variety of biological processes, such as cell signaling, regulatory networks, immune responses, and enzyme inhibition. Peptides are characterized by low...
9.
Santana C, de A Silveira S, Moraes J, Izidoro S, C de Melo-Minardi R, Ribeiro A, et al.
Bioinformatics
. 2020 Dec;
36(Suppl_2):i726-i734.
PMID: 33381849
Motivation: The discovery of protein-ligand-binding sites is a major step for elucidating protein function and for investigating new functional roles. Detecting protein-ligand-binding sites experimentally is time-consuming and expensive. Thus, a...
10.
Barroso J, Mariano D, Dias S, Rocha R, Santos L, Nagem R, et al.
BMC Bioinformatics
. 2020 Jul;
21(1):275.
PMID: 32611389
Background: Protein engineering has many applications for industry, such as the development of new drugs, vaccines, treatment therapies, food, and biofuel production. A common way to engineer a protein is...