Raphael Pelossof
Overview
Explore the profile of Raphael Pelossof including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
16
Citations
665
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0
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Recent Articles
11.
Chow O, Kuk D, Keskin M, Smith J, Camacho N, Pelossof R, et al.
Ann Surg Oncol
. 2016 Mar;
23(8):2548-55.
PMID: 27020587
Background: The response of rectal cancers to neoadjuvant chemoradiation (CRT) is variable, but tools to predict response remain lacking. We evaluated whether KRAS and TP53 mutations are associated with pathologic...
12.
Pelossof R, Chow O, Garcia-Aguilar J
Genes Chromosomes Cancer
. 2016 Mar;
55(7):613.
PMID: 27015446
No abstract available.
13.
Pelossof R, Chow O, Fairchild L, Smith J, Setty M, Chen C, et al.
Genes Chromosomes Cancer
. 2016 Feb;
55(4):311-321.
PMID: 26865277
Locally advanced rectal cancer (LARC) is treated with chemoradiation prior to surgical excision, leaving residual tumors altered or completely absent. Integrating layers of genomic profiling might identify regulatory pathways relevant...
14.
Pelossof R, Singh I, Yang J, Weirauch M, Hughes T, Leslie C
Nat Biotechnol
. 2015 Nov;
33(12):1242-1249.
PMID: 26571099
Predicting the affinity profiles of nucleic acid-binding proteins directly from the protein sequence is a challenging problem. We present a statistical approach for learning the recognition code of a family...
15.
Osmanbeyoglu H, Pelossof R, Bromberg J, Leslie C
Genome Res
. 2014 Sep;
24(11):1869-80.
PMID: 25183703
Cancer cells acquire genetic and epigenetic alterations that often lead to dysregulation of oncogenic signal transduction pathways, which in turn alters downstream transcriptional programs. Numerous methods attempt to deduce aberrant...
16.
Fennell M, Xiang Q, Hwang A, Chen C, Huang C, Chen C, et al.
J Biomol Screen
. 2014 Aug;
19(10):1327-37.
PMID: 25163683
For well over a decade, RNA interference (RNAi) has provided a powerful tool for investigators to query specific gene targets in an easily modulated loss-of-function setting, both in vitro and...