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Raphael Guerois

Explore the profile of Raphael Guerois including associated specialties, affiliations and a list of published articles. Areas
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Articles 119
Citations 3587
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Recent Articles
1.
Novikov N, Gao J, Fokin A, Rocques N, Chiappetta G, Rysenkova K, et al.
Nat Commun . 2025 Jan; 16(1):205. PMID: 39747206
The molecular mechanisms underlying cell migration remain incompletely understood. Here, we show that knock-out cells for NHSL3, the most recently identified member of the Nance-Horan Syndrome family, are more persistent...
2.
Dalia T, Machouri M, Lacrouts C, Fauconnet Y, Guerois R, Andreani J, et al.
bioRxiv . 2024 Nov; PMID: 39484419
Significance Statement: Bacteria can acquire novel traits like antibiotic resistance and virulence through horizontal gene transfer by natural transformation. During this process, cells take up free DNA from the environment...
3.
Ceppi I, Dello Stritto M, Mutze M, Braunshier S, Mengoli V, Reginato G, et al.
Nature . 2024 Sep; 634(8033):492-500. PMID: 39261728
DNA double-strand break (DSB) repair by homologous recombination is initiated by DNA end resection, a process involving the controlled degradation of the 5'-terminated strands at DSB sites. The breast cancer...
4.
Nicolas Y, Bret H, Cannavo E, Acharya A, Cejka P, Borde V, et al.
Mol Cell . 2024 Jun; 84(12):2223-2237.e4. PMID: 38870937
In Saccharomyces cerevisiae (S. cerevisiae), Mre11-Rad50-Xrs2 (MRX)-Sae2 nuclease activity is required for the resection of DNA breaks with secondary structures or protein blocks, while in humans, the MRE11-RAD50-NBS1 (MRN) homolog...
5.
Acharya A, Bret H, Huang J, Mutze M, Gose M, Kissling V, et al.
Nat Commun . 2024 Apr; 15(1):3584. PMID: 38678026
HROB promotes the MCM8-9 helicase in DNA damage response. To understand how HROB activates MCM8-9, we defined their interaction interface. We showed that HROB makes important yet transient contacts with...
6.
Ouasti F, Audin M, Freon K, Quivy J, Tachekort M, Cesard E, et al.
Elife . 2024 Feb; 12. PMID: 38376141
Genome and epigenome integrity in eukaryotes depends on the proper coupling of histone deposition with DNA synthesis. This process relies on the evolutionary conserved histone chaperone CAF-1 for which the...
7.
Leuzzi G, Vasciaveo A, Taglialatela A, Chen X, Firestone T, Hickman A, et al.
Cell . 2024 Feb; 187(4):861-881.e32. PMID: 38301646
Genomic instability can trigger cancer-intrinsic innate immune responses that promote tumor rejection. However, cancer cells often evade these responses by overexpressing immune checkpoint regulators, such as PD-L1. Here, we identify...
8.
Bret H, Gao J, Zea D, Andreani J, Guerois R
Nat Commun . 2024 Jan; 15(1):597. PMID: 38238291
The revolution brought about by AlphaFold2 opens promising perspectives to unravel the complexity of protein-protein interaction networks. The analysis of interaction networks obtained from proteomics experiments does not systematically provide...
9.
Liu S, Mine-Hattab J, Villemeur M, Guerois R, Pinholt H, Mirny L, et al.
Nat Struct Mol Biol . 2023 Nov; 30(12):2020. PMID: 37993685
No abstract available.
10.
Vrielynck N, Peuch M, Durand S, Lian Q, Chambon A, Hurel A, et al.
Nat Plants . 2023 Nov; 9(12):2016-2030. PMID: 37973938
The synaptonemal complex (SC) is a proteinaceous structure that forms between homologous chromosomes during meiosis prophase. The SC is widely conserved across species, but its structure and roles during meiotic...