Raphael Cornu
Overview
Explore the profile of Raphael Cornu including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
58
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Recent Articles
1.
Antoine T, Beduneau A, Chretien C, Cornu R, Bonnefoy F, Moulari B, et al.
Int J Pharm
. 2024 Dec;
669():125062.
PMID: 39653295
Inflammatory Bowel Diseases (IDB) are chronic disorders characterized by gut inflammation, mucosal damage, increased epithelial permeability and altered mucus layer. No accurate in vitro model exists to simulate these characteristics....
2.
Stalder T, Koenig N, Cornu R, Laurent G, Pellequer Y, Jurin F, et al.
Eur J Pharm Biopharm
. 2024 Nov;
206:114588.
PMID: 39613271
Oral administration of siRNA is a challenging strategy for the local treatment of intestinal diseases, including cancer and inflammatory bowel disease. Both nucleic acids and delivery systems, especially lipid nanoparticles...
3.
El Basset W, Cornu R, Zaiter T, Jacquin L, Pellequer Y, Moulari B, et al.
Nanotoxicology
. 2024 Aug;
18(5):499-510.
PMID: 39207115
Polyethylene (PE) is one of the most widely used plastics in the world. Its degradation leads to the production of small particles including microplastics and nanoplastics (NPs). Plastic particles' presence...
4.
Dakhlaoui I, Bernard P, Pietrzak D, Simakov A, Maj M, Refouvelet B, et al.
Int J Mol Sci
. 2023 Jun;
24(11).
PMID: 37298693
Alzheimer's disease (AD) is a multifactorial neurodegenerative disease that has a heavy social and economic impact on all societies and for which there is still no cure. Multitarget-directed ligands (MTDLs)...
5.
Stalder T, Zaiter T, El-Basset W, Cornu R, Martin H, Diab-Assaf M, et al.
Toxicology
. 2022 Oct;
481:153353.
PMID: 36257551
The gastrointestinal tract represents one of primary routes of entry for many nanomaterials. Their size in the nanometer range and their high surface area confer them very interesting properties as...
6.
Cornu R, Beduneau A, Martin H
Arch Toxicol
. 2022 Jul;
96(10):2655-2686.
PMID: 35895099
Titanium dioxide (TiO) is one of the most commonly used nanomaterials in the world. Additive E171, which is used in the food industry, contains a nanometric particle fraction of TiO....
7.
Zaiter T, Cornu R, Millot N, Herbst M, Pellequer Y, Moarbess G, et al.
Nanotoxicology
. 2022 May;
16(2):165-182.
PMID: 35579945
The E551 food additive is composed of synthetic amorphous silica particles. The current regulation does not mention any specifications regarding their size and granulometric distribution, thus allowing the presence of...
8.
Pham D, Saelim N, Cornu R, Beduneau A, Tiyaboonchai W
Pharmaceuticals (Basel)
. 2020 May;
13(5).
PMID: 32366020
Recently, crosslinked fibroin nanoparticles (FNP) using the crosslinker 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) or the polymer poly(ethylenimine) (PEI) have been developed and showed potentials as novel drug delivery systems. Thus, this...
9.
Cornu R, Chretien C, Pellequer Y, Martin H, Beduneau A
Arch Toxicol
. 2020 Mar;
94(4):1191-1202.
PMID: 32162006
Amorphous silica nanoparticles are widely used as pharmaceutical excipients and food additive (E551). Despite the potential human health risks of mineral nanoparticles, very few data regarding their oral toxicity are...
10.
Cornu R, Beduneau A, Martin H
Toxicology
. 2019 Dec;
430:152344.
PMID: 31843632
Due to the increasing interest in nanotechnology in very large application fields, including biotechnology, electronics and food industries, humans are increasingly exposed to nanoparticles (NPs). Consequently, the question about the...