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Ranjan J Perera

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Recent Articles
1.
Joshi K, Yuan M, Katsushima K, Saulnier O, Ray A, Amankwah E, et al.
Res Sq . 2024 Sep; PMID: 39281885
Medulloblastoma, the most common malignant pediatric brain tumor, is classified into four main molecular subgroups, but group 3 and group 4 tumors are difficult to subclassify and have a poor...
2.
Joshi K, Yuan M, Katsushima K, Saulnier O, Ray A, Amankwah E, et al.
Acta Neuropathol Commun . 2024 Aug; 12(1):138. PMID: 39198884
Medulloblastoma, the most common malignant pediatric brain tumor, is classified into four main molecular subgroups, but group 3 and group 4 tumors are difficult to subclassify and have a poor...
3.
Liang W, Liu W, Xiong X, Li J, Li J, Perera R, et al.
Cell Rep . 2024 Mar; 43(4):113973. PMID: 38507406
We identified and validated a collection of circular RNAs (circRNAs) in Drosophila melanogaster. We show that depletion of the pro-viral circRNA circATP8B(2), but not its linear siblings, compromises viral infection...
4.
Katsushima K, Joshi K, Yuan M, Romero B, Batish M, Stapleton S, et al.
Cell Rep . 2024 Mar; 43(3):113938. PMID: 38460130
Recent studies suggest that long non-coding RNAs (lncRNAs) contribute to medulloblastoma (MB) formation and progression. We have identified an lncRNA, lnc-HLX-2-7, as a potential therapeutic target in group 3 (G3)...
5.
Yuan M, Mahmud I, Katsushima K, Joshi K, Saulnier O, Pokhrel R, et al.
Acta Neuropathol Commun . 2023 Dec; 11(1):203. PMID: 38115140
The prognosis of childhood medulloblastoma (MB) is often poor, and it usually requires aggressive therapy that adversely affects quality of life. microRNA-211 (miR-211) was previously identified as an important regulator...
6.
Alahdal M, Perera R, Moschovas M, Patel V, Perera R
Mol Ther Oncolytics . 2023 Aug; 30:27-38. PMID: 37575217
Prostate cancer (PCa) incidence is increasing and endangers men's lives. Early detection of PCa could improve overall survival (OS) by preventing metastasis. The prostate-specific antigen (PSA) test is a popular...
7.
Katsushima K, Joshi K, Perera R
Neurooncol Adv . 2023 Jun; 5(1):vdad063. PMID: 37334165
Circular RNAs (circRNAs) are a class of RNA with a stable cyclic structure. They are expressed in various tissues and cells with conserved, specific characteristics. CircRNAs have been found to...
8.
Katsushima K, Pokhrel R, Mahmud I, Yuan M, Murad R, Baral P, et al.
Acta Neuropathol Commun . 2023 Mar; 11(1):38. PMID: 36899402
Medulloblastoma (MB) develops through various genetic, epigenetic, and non-coding (nc) RNA-related mechanisms, but the roles played by ncRNAs, particularly circular RNAs (circRNAs), remain poorly defined. CircRNAs are increasingly recognized as...
9.
Xiong X, Liang W, Liu W, Xu S, Li J, Tito A, et al.
PLoS Genet . 2022 Oct; 18(10):e1010429. PMID: 36301822
Circular RNAs (circRNAs) are widely expressed in eukaryotes. However, only a subset has been functionally characterized. We identify and validate a collection of circRNAs in Drosophila, and show that depletion...
10.
Lee B, Katsushima K, Pokhrel R, Yuan M, Stapleton S, Jallo G, et al.
Neurooncol Adv . 2022 Oct; 4(1):vdac120. PMID: 36267874
Background: Although some of the regulatory genes, signaling pathways, and gene regulatory networks altered in medulloblastomas (MB) are known, the roles of non-coding RNAs, particularly long non-coding RNAs (lncRNAs), are...