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Randy S Longman

Explore the profile of Randy S Longman including associated specialties, affiliations and a list of published articles. Areas
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Articles 51
Citations 4346
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Recent Articles
11.
Gordon B, Galati J, Yang S, Longman R, Lukin D, Scherl E, et al.
World J Gastroenterol . 2022 Sep; 28(33):4834-4845. PMID: 36156920
Background: Patients with inflammatory bowel disease (IBD) are prone to several nutritional deficiencies. However, data are lacking on vitamin C deficiency in Crohn's disease (CD) and ulcerative colitis (UC) patients,...
12.
Zegarra Ruiz D, Kim D, Norwood K, Saldana-Morales F, Kim M, Ng C, et al.
Gut Microbes . 2022 Sep; 14(1):2119054. PMID: 36062329
Inflammatory bowel disease (IBD) is a chronic life-long inflammatory disease affecting almost 2 million Americans. Although new biologic therapies have been developed, the standard medical treatment fails to selectively control...
13.
Angkeow J, Monaco D, Chen A, Venkataraman T, Jayaraman S, Valencia C, et al.
Immunity . 2022 Jun; 55(6):1051-1066.e4. PMID: 35649416
Microbial exposures are crucial environmental factors that impact healthspan by sculpting the immune system and microbiota. Antibody profiling via Phage ImmunoPrecipitation Sequencing (PhIP-Seq) provides a high-throughput, cost-effective approach for detecting...
14.
Paik D, Yao L, Zhang Y, Bae S, DAgostino G, Zhang M, et al.
Nature . 2022 Mar; 603(7903):907-912. PMID: 35296854
The microbiota modulates gut immune homeostasis. Bacteria influence the development and function of host immune cells, including T helper cells expressing interleukin-17A (T17 cells). We previously reported that the bile ...
15.
Battat R, Galati J, Lukin D, Chabouni F, Sockolow R, Carter J, et al.
J Clin Gastroenterol . 2022 Feb; 56(3):e176-e182. PMID: 35180182
Background: Delays in biologic or small molecule medication administration are associated with increased adverse events, hospitalization, and surgery in inflammatory bowel disease (IBD). We evaluated the impact of a quality...
16.
Jin W, Li T, Huo D, Qu S, Li X, Arifuzzaman M, et al.
Cell . 2022 Jan; 185(3):547-562.e22. PMID: 35051369
Hundreds of microbiota genes are associated with host biology/disease. Unraveling the causal contribution of a microbiota gene to host biology remains difficult because many are encoded by nonmodel gut commensals...
17.
Charilaou P, Tricarico C, Battat R, Scherl E, Longman R, Lukin D
Clin Gastroenterol Hepatol . 2021 Dec; 20(6):e1493-e1499. PMID: 34896283
Immunization against the spike protein of SARS-CoV-2 reduces transmission and severe outcomes. However, little is known regarding the impact of immune-mediated diseases and immunosuppressive medications on the efficacy of vaccination....
18.
Doron I, Mesko M, Li X, Kusakabe T, Leonardi I, Shaw D, et al.
Nat Microbiol . 2021 Nov; 6(12):1493-1504. PMID: 34811531
Secretory immunoglobulin A (sIgA) plays an important role in gut barrier protection by shaping the resident microbiota community, restricting the growth of bacterial pathogens and enhancing host protective immunity via...
19.
Lima S, Longman R
J Crohns Colitis . 2021 Oct; 16(3):341-342. PMID: 34718490
No abstract available.
20.
Lima S, Gogokhia L, Viladomiu M, Chou L, Putzel G, Jin W, et al.
Gastroenterology . 2021 Oct; 162(1):166-178. PMID: 34606847
Background & Aims: Fecal microbiota transplantation (FMT) is an emerging treatment modality for ulcerative colitis (UC). Several randomized controlled trials have shown efficacy for FMT in the treatment of UC,...