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Randolph R Singh

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Articles 19
Citations 168
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Recent Articles
1.
Heins-Marroquin U, Singh R, Perathoner S, Gavotto F, Merino Ruiz C, Patraskaki M, et al.
Life Sci Alliance . 2024 Jan; 7(3). PMID: 38195117
Juvenile neuronal ceroid lipofuscinosis (or Batten disease) is an autosomal recessive, rare neurodegenerative disorder that affects mainly children above the age of 5 yr and is most commonly caused by...
2.
Singh R, Aminot Y, Heas-Moisan K, Preudhomme H, Munschy C
Environ Int . 2023 Jul; 178:108094. PMID: 37478678
High resolution mass spectrometry (HRMS)-based non-target analysis coupled with ion mobility spectrometry (IMS) is gaining momentum due to its ability to provide complementary information which can be useful in the...
3.
Elapavalore A, Kondic T, Singh R, Shoemaker B, Thiessen P, Zhang J, et al.
Environ Sci Process Impacts . 2023 Jul; 25(11):1788-1801. PMID: 37431591
The term "exposome" is defined as a comprehensive study of life-course environmental exposures and the associated biological responses. Humans are exposed to many different chemicals, which can pose a major...
4.
Singh R, Lai A, Krier J, Kondic T, Diderich P, Schymanski E
ACS Environ Au . 2023 Apr; 1(1):58-70. PMID: 37101936
Pharmaceuticals and their transformation products (TPs) are continuously released into the aquatic environment via anthropogenic activity. To expand knowledge on the presence of pharmaceuticals and their known TPs in Luxembourgish...
5.
Geyer K, Hartmann S, Singh R, Erb T
Biochemistry . 2022 Nov; 61(23):2662-2671. PMID: 36378762
Polyketide synthases (PKSs) are molecular assembly lines that condense basic chemical building blocks for the production of structurally diverse polyketides. Many PKS biosynthetic gene clusters contain a gene encoding for...
6.
Mohammed Taha H, Aalizadeh R, Alygizakis N, Antignac J, Arp H, Bade R, et al.
Environ Sci Eur . 2022 Oct; 34(1):104. PMID: 36284750
Background: The NORMAN Association (https://www.norman-network.com/) initiated the NORMAN Suspect List Exchange (NORMAN-SLE; https://www.norman-network.com/nds/SLE/) in 2015, following the NORMAN collaborative trial on non-target screening of environmental water samples by mass spectrometry....
7.
Andujar B, Aurich D, Aho V, Singh R, Cheng T, Zaslavsky L, et al.
Anal Bioanal Chem . 2022 Jul; 414(25):7399-7419. PMID: 35829770
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease, with an increasing incidence in recent years due to the aging population. Genetic mutations alone only explain <10% of PD...
8.
Krier J, Singh R, Kondic T, Lai A, Diderich P, Zhang J, et al.
Environ Int . 2021 Sep; 158:106885. PMID: 34560325
The diversity of hundreds of thousands of potential organic pollutants and the lack of (publicly available) information about many of them is a huge challenge for environmental sciences, engineering, and...
9.
Angeles L, Singh R, Vikesland P, Aga D
J Hazard Mater . 2021 Mar; 414:125369. PMID: 33647625
Suspect screening using liquid chromatography with high resolution mass spectrometry provides an opportunity for expanding the detection coverage of emerging contaminants in the environment. Screening workflows may suffer from high...
10.
Singh R, Chao A, Phillips K, Xia X, Shea D, Sobus J, et al.
Anal Bioanal Chem . 2020 Jun; 412(20):4931-4939. PMID: 32494915
Non-targeted analysis (NTA) is a rapidly evolving analytical technique with numerous opportunities to improve and expand instrumental and data analysis methods. In this work, NTA was performed on eight synthetic...