Rana Herro
Overview
Explore the profile of Rana Herro including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
354
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Recent Articles
1.
Herro R, Grimes H
Nat Immunol
. 2024 Nov;
25(12):2209-2219.
PMID: 39567761
Neutrophil granulocytes are the most abundant leukocytes in the blood and constitute a critical arm of innate immunity. They are generated in the bone marrow, and under homeostatic conditions enter...
2.
Steele H, Cheng J, Willicut A, Dell G, Breckenridge J, Culberson E, et al.
Front Immunol
. 2023 Jul;
14:1219907.
PMID: 37465675
Fibrosis is the result of extracellular matrix protein deposition and remains a leading cause of death in USA. Despite major advances in recent years, there remains an unmet need to...
3.
Miki H, Kiosses W, Manresa M, Gupta R, Sethi G, Herro R, et al.
J Allergy Clin Immunol
. 2022 Dec;
151(4):976-990.e5.
PMID: 36473503
Background: Dysregulation of airway smooth muscle cells (ASM) is central to the severity of asthma. Which molecules dominantly control ASM in asthma is unclear. High levels of the cytokine LIGHT...
4.
Manresa M, Miki H, Miller J, Okamoto K, Dobaczewska K, Herro R, et al.
J Immunol
. 2022 Nov;
PMID: 36426994
Eosinophilic esophagitis (EoE) is a chronic type 2 allergic disease, with esophageal tissue remodeling as the mechanism behind clinical dysphagia and strictures. IL-13 is thought to be a central driver...
5.
Manresa M, Miki H, Miller J, Okamoto K, Dobaczewska K, Herro R, et al.
J Immunol
. 2022 Oct;
PMID: 36288906
Eosinophilic esophagitis (EoE) is a chronic type 2 allergic disease, with esophageal tissue remodeling as the mechanism behind clinical dysphagia and strictures. IL-13 is thought to be a central driver...
6.
Bone Marrow Transplantation Rescues Monocyte Recruitment Defect and Improves Cystic Fibrosis in Mice
Fan Z, Pitmon E, Wen L, Miller J, Ehinger E, Herro R, et al.
J Immunol
. 2022 Jan;
208(3):745-752.
PMID: 35031577
Cystic fibrosis (CF) is an inherited life-threatening disease accompanied by repeated lung infections and multiorgan inflammation that affects tens of thousands of people worldwide. The causative gene, cystic fibrosis transmembrane...
7.
Steele H, Song B, Willicut A, Grimes H, Herro R
J Immunol Methods
. 2021 Aug;
497:113107.
PMID: 34352237
Understanding the interplay between immune and structural cells is important for studying fibrosis and inflammation; however, primary immune cell isolation from organs that are typically enriched in stromal cells, like...
8.
Steele H, Sachen K, McKnight A, Soloff R, Herro R
Front Immunol
. 2021 Jul;
12:692127.
PMID: 34305924
Mucus secretion is an important feature of asthma that highly correlates with morbidity. Current therapies, including administration of mucolytics and anti-inflammatory drugs, show limited effectiveness and durability, underscoring the need...
9.
Herro R, Miki H, Sethi G, Mills D, Mehta A, Nguyen X, et al.
J Immunol
. 2020 Sep;
205(9):2414-2422.
PMID: 32958689
Lung fibrosis and tissue remodeling are features of chronic diseases such as severe asthma, idiopathic pulmonary fibrosis, and systemic sclerosis. However, fibrosis-targeted therapies are currently limited. We demonstrate in mouse...
10.
Manresa M, Chiang A, Kurten R, Dohil R, Brickner H, Dohil L, et al.
Gastroenterology
. 2020 Jul;
159(5):1778-1792.e13.
PMID: 32712105
Background & Aims: Eosinophilic esophagitis (EoE) is an antigen-mediated eosinophilic disease of the esophagus that involves fibroblast activation and progression to fibrostenosis. Cytokines produced by T-helper type 2 cells and...