Ramona Businger
Overview
Explore the profile of Ramona Businger including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
177
Followers
0
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Recent Articles
1.
Syrigos G, Feige M, Dirlam A, Businger R, Gruska I, Wiebusch L, et al.
Antiviral Res
. 2023 Jul;
217:105689.
PMID: 37516154
Human cytomegalovirus (HCMV) is a herpesvirus that causes life-threatening infections in newborns or immunosuppressed patients. For viral replication, HCMV establishes a network of cellular interactions, among others cyclin-dependent kinases (CDK)....
2.
Bayyoud T, Syrigos G, Ruetalo Buschinger N, Wude J, Businger R, Hu D, et al.
Graefes Arch Clin Exp Ophthalmol
. 2022 Aug;
261(2):435-446.
PMID: 35920896
Purpose: To study the possibility of SARS-CoV-2 to infect human corneal cells and tissues under standard corneal culture conditions using explants of COVID-19 donors and primary cornea-derived epithelial cells. Methods:...
3.
Ruetalo N, Businger R, Schindler M
Euro Surveill
. 2021 Oct;
26(42).
PMID: 34676820
Background: The COVID-19 pandemic urges for cheap, reliable, and rapid technologies for disinfection and decontamination. One frequently proposed method is ultraviolet (UV)-C irradiation. UV-C doses necessary to achieve inactivation of...
4.
Hochdorfer D, Businger R, Hotter D, Seifried C, Solzin J
J Virol Methods
. 2021 Oct;
299:114318.
PMID: 34626683
A robust and precise infectivity assay is a prerequisite for the development and market supply of virus-based biologics. Like other cell-based assays, traditional infectivity assays suffer from high variability and...
5.
Businger R, Kivimaki S, Simeonov S, Syrigos G, Pohlmann J, Bolz M, et al.
mBio
. 2021 Aug;
12(4):e0177021.
PMID: 34399625
The plasma membrane (PM) must be overcome by viruses during entry and release. Furthermore, the PM represents the cellular communication compartment and the immune system interface. Hence, viruses have evolved...
6.
Grosse M, Ruetalo N, Layer M, Hu D, Businger R, Rheber S, et al.
Viruses
. 2021 Apr;
13(4).
PMID: 33918670
While vaccination campaigns are ongoing worldwide, there is still a tremendous medical need for efficient antivirals against SARS-CoV-2 infection. Among several drug candidates, chloroquine (CQN) and hydroxychloroquine (H-CQN) were tested...
7.
Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients
Ruetalo N, Businger R, Althaus K, Fink S, Ruoff F, Pogoda M, et al.
mSphere
. 2021 Feb;
6(1).
PMID: 33627511
The majority of infections with SARS-CoV-2 are asymptomatic or mild without the necessity of hospitalization. It is of importance to reveal if these patients develop an antibody response against SARS-CoV-2...
8.
Flehmig B, Schindler M, Ruetalo N, Businger R, Bayer M, Haage A, et al.
Viruses
. 2020 Dec;
12(12).
PMID: 33260809
The relationship between the nasopharyngeal virus load, IgA and IgG antibodies to both the S1-RBD-protein and the N-protein, as well as the neutralizing activity (NAbs) against SARS-CoV-2 in the blood...
9.
Boffert R, Businger R, Preiss H, Ehmann D, Truffault V, Simon C, et al.
Antiviral Res
. 2020 Mar;
177:104779.
PMID: 32209394
Human cytomegalovirus (HCMV) infection causes severe illness in newborns and immunocompromised patients. Since treatment options are limited there is an unmet need for new therapeutic approaches. Defensins are cationic peptides,...
10.
Businger R, Deutschmann J, Gruska I, Milbradt J, Wiebusch L, Gramberg T, et al.
Nat Microbiol
. 2019 Sep;
4(12):2260-2272.
PMID: 31548682
The host restriction factor sterile alpha motif and histidine-aspartate domain-containing protein 1 (SAMHD1) is an important component of the innate immune system. By regulating the intracellular nucleotide pool, SAMHD1 influences...